Topical formulation of a new plant extract complex with refirming properties. Clinical and non-invasive evaluation in a double-blind trial

L. Martelli, E. Berardesca, M. Martelli

Research output: Contribution to journalArticle

Abstract

We tested an OTC formulation versus placebo in a double-blind trial to evaluate its ability to improve elasticity and firmness of the skin. The clinical non-invasive evaluation in 20 volunteers shows: 1. No adverse reactions such as itching or irritation. 2. Efficacy and cosmetic acceptibility of the test cream. 3. An increase in electrical capacitance (moisture content) even though without statistical significance. This result is not surprising because the patients had healthy skin and were relatively young (aged 20-25). 4. A very significant improvement in the biomechanical properties (extensibility and firmness) of the skin. This increase was statistically significant (P <0.02). The main components of the cream (boswellic acids, Sylibin and Centella asiatica extracts) were formulated as complexes with lyso-phospholipids and soya bean non-saponifiable lipids.

Original languageEnglish
Pages (from-to)201-206
Number of pages6
JournalInternational Journal of Cosmetic Science
Volume22
Issue number3
DOIs
Publication statusPublished - 2000

Keywords

  • Ageing
  • Boswellia serrata
  • Centella asiatica extracts
  • In vivo study
  • Phospholipids
  • Silybum marianum
  • Topical application
  • Wrinkles and striae

ASJC Scopus subject areas

  • Chemistry (miscellaneous)
  • Dermatology

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