Topical immunomodulators for the treatment of external genital warts, cutaneous warts and molluscum contagiosum

U. R. Hengge, M. Cusini

Research output: Contribution to journalArticlepeer-review

Abstract

Topical immunomodulators (TIMs) include both immunostimulatory and immunosuppressive agents. Newer immunostimulatory compounds such as imidazoquinolines (e.g. imiquimod) act by cytokine secretion from monocytes/macrophages (interferon-α, interleukin-12, tumour-necrosis factor-α), leading to a Th1-dominance and cell-mediated immunity. This immune milieu has been clinically used to treat viral infections such as human papillomavirus (condyloma and common warts), herpes simplex virus and mollusca in immunocompetent and immunosuppressed patients.

Original languageEnglish
Pages (from-to)15-19
Number of pages5
JournalBritish Journal of Dermatology, Supplement
Volume149
Issue number66
Publication statusPublished - Nov 2003

Keywords

  • Human papillomavirus
  • Imiquimod
  • Molluscum contagiosum
  • Topical immunomodulators

ASJC Scopus subject areas

  • Dermatology

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