Topiramate efficacy in an infant with partial seizures refractory to conventional antiepileptic drugs

Pierangelo Veggiotti, Francesca Longaretti, Sabrina Signorini, Simonetta Cardinali, Giovanni Lanzi

Research output: Contribution to journalArticle

Abstract

Many studies showed that Topiramate (TPM) may be a useful drug in a wide spectrum of childhood epilepsies. We report a 3-month-old female with stormy onset of secondarily generalized partial seizures. She showed a high seizure frequency and a progressive worsening electroencephalogram (EEG), despite standard antiepileptic drugs administration. TPM succeeded in controlling seizures, even after the other drugs were discontinued. This case suggests that TPM may represent a good choice for the treatment of partial seizures refractory to conventional drugs in infants.

Original languageEnglish
Pages (from-to)241-243
Number of pages3
JournalSeizure
Volume13
Issue number4
DOIs
Publication statusPublished - Jun 2004

Keywords

  • Drug-resistant
  • Efficacy
  • Infancy
  • Partial seizures
  • Topiramate

ASJC Scopus subject areas

  • Clinical Neurology
  • Pediatrics, Perinatology, and Child Health
  • Neurology
  • Psychology(all)

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