Il topiramato nel trattamento dell'epilessia farmacoresistente: Risultati di uno studio a lungo termine

Translated title of the contribution: Topiramate in the treatment of drug-resistant epilepsy: A long-term follow-up study

R. Michelucci, D. Passarelli, M. Di Fazio, C. A. Tassinari

Research output: Contribution to journalArticlepeer-review

Abstract

We investigated the long-term efficacy and tolerability of add-on Topiramate, used under placebo- controlled conditions, in 13 adult refractory epileptic patients, mostly with complex partial seizures. Overall, 4 patients (33%) were still on Topiramate (400 to 1000 mg/daily) after a mean period of 30 months. CNS-related side effects occurred in 10 patients and were usually transitory and mild. We conclude that Topiramate maintains its benefit on long-term follow-up in one third of the patients initially exposed to the study drug.

Translated title of the contributionTopiramate in the treatment of drug-resistant epilepsy: A long-term follow-up study
Original languageItalian
Pages (from-to)255-256
Number of pages2
JournalBollettino - Lega Italiana contro l'Epilessia
Issue number95-96
Publication statusPublished - 1996

ASJC Scopus subject areas

  • Clinical Neurology

Fingerprint

Dive into the research topics of 'Topiramate in the treatment of drug-resistant epilepsy: A long-term follow-up study'. Together they form a unique fingerprint.

Cite this