Topological map of the body in post-stroke patients: Lesional and hodological aspects

Antonella Di Vita, Liana Palermo, Maddalena Boccia, Cecilia Guariglia

Research output: Contribution to journalArticle

Abstract

Objective: It has been repeatedly hypothesized that at least 3 distinct types of body representations do exist: body schema, a representation derived from multiple sensory and motor inputs; topological map of the body, a structural description of spatial relations among the body parts; and body semantics, a lexical-semantic representation. Although several studies have assessed neural correlates of the topological map of the body in healthy participants, a systematic investigation of neural underpinnings of the topological map of the body in brain-damaged patients is still lacking. Method: Here we investigated the neural substrates of topological map of the body in 23 brain-damaged patients, both from a topological and an hodological perspectives, using Voxel Lesion Symptom Mapping and atlas-based track-wise statistical analysis. Besides neuroimaging investigation, consisting of T1-weighted and FLAIR sequences, patients underwent the frontal body-evocation subtest (FBE) to assess the topological map of the body. Results: The present results reveal a large-scale brain network involved in the topological map of the body assessed with FBE, encompassing both regions of primary elaboration and multisensory associative areas, in the temporal, parietal, frontal, and insular cortices. Hodological analysis revealed significant association between processing of the body topological map and the disconnection of the frontomarginal tract. Conclusions: These findings suggest that the topological map of the body is built up basing on both external and internal information that comes from the body and are constantly updated and integrated. The theoretical and clinical relevance of these results is discussed.

Original languageEnglish
Pages (from-to)499-507
Number of pages9
JournalNeuropsychology
Volume33
Issue number4
DOIs
Publication statusPublished - May 1 2019

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Body Image
Stroke
Semantics
Brain
Parietal Lobe
Atlases
Frontal Lobe
Temporal Lobe
Human Body
Neuroimaging
Cerebral Cortex
Healthy Volunteers

Keywords

  • Body representation
  • Body schema
  • Topological map of the body
  • VLSM

ASJC Scopus subject areas

  • Neuropsychology and Physiological Psychology

Cite this

Topological map of the body in post-stroke patients : Lesional and hodological aspects. / Di Vita, Antonella; Palermo, Liana; Boccia, Maddalena; Guariglia, Cecilia.

In: Neuropsychology, Vol. 33, No. 4, 01.05.2019, p. 499-507.

Research output: Contribution to journalArticle

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