Tortuosity of the descending thoracic aorta: Normal values by age

Viony M. Belvroy, Hector W.L. De Beaufort, Joost A. Van Herwaarden, Jean Bismuth, Frans L. Moll, Santi Trimarchi

Research output: Contribution to journalArticle

Abstract

Background Aging changes the aorta in length, tortuosity and diameter. This is relevant in thoracic endovascular aortic repair (TEVAR) and in the long term follow up. Methods and results Two groups of hundred patients < 65 years and hundred patients 65 years, with no vascular diseases were made. Thin cut CT scans were analyzed with 3Mensio Vascular software and the following measurements were collected; tortuosity index, curvature ratio, maximum tortuosity in degrees and the level of vertebrae of the maximum tortuosity. The descending thoracic aorta (DTA) was analyzed and was divided into four zones of equal length. Subjects were divided into three groups based on their maximum tortuosity value: low (< 30), moderate (30 – 60) and high (> 60). A linear regression model was built to test the effect of age and gender on tortuosity. Tortuosity was more pronounced in the 65 compared to the < 65 group (tortuosity index: 1.05 vs. 1.14, respectively; p < 0.001), curvature ratio (1.00 vs. 1.01; p < 0.001), maximum tortuosity (22.24 vs. 27.26; p < 0.001), and group of angulation (low vs. low; p < 0.001). Additionally, the location of maximum tortuosity was further distal for the 65 group (level of vertebrae; 5.00 vs. 5.00; p < 0.001), and zone of maximum tortuosity (4A vs. 4A; p < 0.001). There was no significant difference between male and female subjects. Conclusion Normal DTA tortuosity increases with age. This is important to understand natural aging and for TEVAR planning and follow-up.

Original languageEnglish
Article numbere0215549
JournalPLoS One
Volume14
Issue number4
DOIs
Publication statusPublished - Apr 1 2019

Fingerprint

chest
aorta
Thoracic Aorta
normal values
Linear Models
Reference Values
Repair
Thorax
Aging of materials
vertebrae
Linear regression
Differential thermal analysis
Aorta
Spine
planning
Planning
gender
testing
methodology

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)

Cite this

Belvroy, V. M., De Beaufort, H. W. L., Van Herwaarden, J. A., Bismuth, J., Moll, F. L., & Trimarchi, S. (2019). Tortuosity of the descending thoracic aorta: Normal values by age. PLoS One, 14(4), [e0215549]. https://doi.org/10.1371/journal.pone.0215549

Tortuosity of the descending thoracic aorta : Normal values by age. / Belvroy, Viony M.; De Beaufort, Hector W.L.; Van Herwaarden, Joost A.; Bismuth, Jean; Moll, Frans L.; Trimarchi, Santi.

In: PLoS One, Vol. 14, No. 4, e0215549, 01.04.2019.

Research output: Contribution to journalArticle

Belvroy, VM, De Beaufort, HWL, Van Herwaarden, JA, Bismuth, J, Moll, FL & Trimarchi, S 2019, 'Tortuosity of the descending thoracic aorta: Normal values by age', PLoS One, vol. 14, no. 4, e0215549. https://doi.org/10.1371/journal.pone.0215549
Belvroy VM, De Beaufort HWL, Van Herwaarden JA, Bismuth J, Moll FL, Trimarchi S. Tortuosity of the descending thoracic aorta: Normal values by age. PLoS One. 2019 Apr 1;14(4). e0215549. https://doi.org/10.1371/journal.pone.0215549
Belvroy, Viony M. ; De Beaufort, Hector W.L. ; Van Herwaarden, Joost A. ; Bismuth, Jean ; Moll, Frans L. ; Trimarchi, Santi. / Tortuosity of the descending thoracic aorta : Normal values by age. In: PLoS One. 2019 ; Vol. 14, No. 4.
@article{977a8920469442c69a2ee71e4ffcb877,
title = "Tortuosity of the descending thoracic aorta: Normal values by age",
abstract = "Background Aging changes the aorta in length, tortuosity and diameter. This is relevant in thoracic endovascular aortic repair (TEVAR) and in the long term follow up. Methods and results Two groups of hundred patients < 65 years and hundred patients 65 years, with no vascular diseases were made. Thin cut CT scans were analyzed with 3Mensio Vascular software and the following measurements were collected; tortuosity index, curvature ratio, maximum tortuosity in degrees and the level of vertebrae of the maximum tortuosity. The descending thoracic aorta (DTA) was analyzed and was divided into four zones of equal length. Subjects were divided into three groups based on their maximum tortuosity value: low (< 30), moderate (30 – 60) and high (> 60). A linear regression model was built to test the effect of age and gender on tortuosity. Tortuosity was more pronounced in the 65 compared to the < 65 group (tortuosity index: 1.05 vs. 1.14, respectively; p < 0.001), curvature ratio (1.00 vs. 1.01; p < 0.001), maximum tortuosity (22.24 vs. 27.26; p < 0.001), and group of angulation (low vs. low; p < 0.001). Additionally, the location of maximum tortuosity was further distal for the 65 group (level of vertebrae; 5.00 vs. 5.00; p < 0.001), and zone of maximum tortuosity (4A vs. 4A; p < 0.001). There was no significant difference between male and female subjects. Conclusion Normal DTA tortuosity increases with age. This is important to understand natural aging and for TEVAR planning and follow-up.",
author = "Belvroy, {Viony M.} and {De Beaufort}, {Hector W.L.} and {Van Herwaarden}, {Joost A.} and Jean Bismuth and Moll, {Frans L.} and Santi Trimarchi",
year = "2019",
month = "4",
day = "1",
doi = "10.1371/journal.pone.0215549",
language = "English",
volume = "14",
journal = "PLoS One",
issn = "1932-6203",
publisher = "Public Library of Science",
number = "4",

}

TY - JOUR

T1 - Tortuosity of the descending thoracic aorta

T2 - Normal values by age

AU - Belvroy, Viony M.

AU - De Beaufort, Hector W.L.

AU - Van Herwaarden, Joost A.

AU - Bismuth, Jean

AU - Moll, Frans L.

AU - Trimarchi, Santi

PY - 2019/4/1

Y1 - 2019/4/1

N2 - Background Aging changes the aorta in length, tortuosity and diameter. This is relevant in thoracic endovascular aortic repair (TEVAR) and in the long term follow up. Methods and results Two groups of hundred patients < 65 years and hundred patients 65 years, with no vascular diseases were made. Thin cut CT scans were analyzed with 3Mensio Vascular software and the following measurements were collected; tortuosity index, curvature ratio, maximum tortuosity in degrees and the level of vertebrae of the maximum tortuosity. The descending thoracic aorta (DTA) was analyzed and was divided into four zones of equal length. Subjects were divided into three groups based on their maximum tortuosity value: low (< 30), moderate (30 – 60) and high (> 60). A linear regression model was built to test the effect of age and gender on tortuosity. Tortuosity was more pronounced in the 65 compared to the < 65 group (tortuosity index: 1.05 vs. 1.14, respectively; p < 0.001), curvature ratio (1.00 vs. 1.01; p < 0.001), maximum tortuosity (22.24 vs. 27.26; p < 0.001), and group of angulation (low vs. low; p < 0.001). Additionally, the location of maximum tortuosity was further distal for the 65 group (level of vertebrae; 5.00 vs. 5.00; p < 0.001), and zone of maximum tortuosity (4A vs. 4A; p < 0.001). There was no significant difference between male and female subjects. Conclusion Normal DTA tortuosity increases with age. This is important to understand natural aging and for TEVAR planning and follow-up.

AB - Background Aging changes the aorta in length, tortuosity and diameter. This is relevant in thoracic endovascular aortic repair (TEVAR) and in the long term follow up. Methods and results Two groups of hundred patients < 65 years and hundred patients 65 years, with no vascular diseases were made. Thin cut CT scans were analyzed with 3Mensio Vascular software and the following measurements were collected; tortuosity index, curvature ratio, maximum tortuosity in degrees and the level of vertebrae of the maximum tortuosity. The descending thoracic aorta (DTA) was analyzed and was divided into four zones of equal length. Subjects were divided into three groups based on their maximum tortuosity value: low (< 30), moderate (30 – 60) and high (> 60). A linear regression model was built to test the effect of age and gender on tortuosity. Tortuosity was more pronounced in the 65 compared to the < 65 group (tortuosity index: 1.05 vs. 1.14, respectively; p < 0.001), curvature ratio (1.00 vs. 1.01; p < 0.001), maximum tortuosity (22.24 vs. 27.26; p < 0.001), and group of angulation (low vs. low; p < 0.001). Additionally, the location of maximum tortuosity was further distal for the 65 group (level of vertebrae; 5.00 vs. 5.00; p < 0.001), and zone of maximum tortuosity (4A vs. 4A; p < 0.001). There was no significant difference between male and female subjects. Conclusion Normal DTA tortuosity increases with age. This is important to understand natural aging and for TEVAR planning and follow-up.

UR - http://www.scopus.com/inward/record.url?scp=85065221620&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85065221620&partnerID=8YFLogxK

U2 - 10.1371/journal.pone.0215549

DO - 10.1371/journal.pone.0215549

M3 - Article

C2 - 31013307

AN - SCOPUS:85065221620

VL - 14

JO - PLoS One

JF - PLoS One

SN - 1932-6203

IS - 4

M1 - e0215549

ER -