Abstract
In hypertensive patients the risk of developing cardiovascular events and complications depends not only on the magnitude of the blood pressure elevation, but also, and to a consistent extent, on the presence of associated cardiovascular risk factors, concomitant disease and target organ damage. Recent findings suggest that also sympathetic overdrive and alterations in blood pressure variability (which are detected in hypertension) may participate at the increased cardiovascular risk of the patients with high blood pressure. This review will discuss the evidence collected over the past few years on the relationships between sympathetic activation and blood pressure variability and their impact on cardiovascular risk profile.
| Original language | English |
|---|---|
| Pages (from-to) | 333-338 |
| Number of pages | 6 |
| Journal | Current Hypertension Reports |
| Volume | 14 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - Aug 2012 |
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Keywords
- Ambulatory blood pressure monitoring
- Blood pressure variability
- Cardiovascular risk
- Cardiovascular risk factors
- Hypertension
- Sympathetic nervous system
ASJC Scopus subject areas
- Internal Medicine
Cite this
Total cardiovascular risk, blood pressure variability and adrenergic overdrive in hypertension : Evidence, mechanisms and clinical implications. / Grassi, Guido; Bombelli, Michele; Brambilla, Gianmaria; Trevano, Fosca Quarti; Dell'Oro, Raffaella; Mancia, Giuseppe.
In: Current Hypertension Reports, Vol. 14, No. 4, 08.2012, p. 333-338.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Total cardiovascular risk, blood pressure variability and adrenergic overdrive in hypertension
T2 - Evidence, mechanisms and clinical implications
AU - Grassi, Guido
AU - Bombelli, Michele
AU - Brambilla, Gianmaria
AU - Trevano, Fosca Quarti
AU - Dell'Oro, Raffaella
AU - Mancia, Giuseppe
PY - 2012/8
Y1 - 2012/8
N2 - In hypertensive patients the risk of developing cardiovascular events and complications depends not only on the magnitude of the blood pressure elevation, but also, and to a consistent extent, on the presence of associated cardiovascular risk factors, concomitant disease and target organ damage. Recent findings suggest that also sympathetic overdrive and alterations in blood pressure variability (which are detected in hypertension) may participate at the increased cardiovascular risk of the patients with high blood pressure. This review will discuss the evidence collected over the past few years on the relationships between sympathetic activation and blood pressure variability and their impact on cardiovascular risk profile.
AB - In hypertensive patients the risk of developing cardiovascular events and complications depends not only on the magnitude of the blood pressure elevation, but also, and to a consistent extent, on the presence of associated cardiovascular risk factors, concomitant disease and target organ damage. Recent findings suggest that also sympathetic overdrive and alterations in blood pressure variability (which are detected in hypertension) may participate at the increased cardiovascular risk of the patients with high blood pressure. This review will discuss the evidence collected over the past few years on the relationships between sympathetic activation and blood pressure variability and their impact on cardiovascular risk profile.
KW - Ambulatory blood pressure monitoring
KW - Blood pressure variability
KW - Cardiovascular risk
KW - Cardiovascular risk factors
KW - Hypertension
KW - Sympathetic nervous system
UR - http://www.scopus.com/inward/record.url?scp=84865649173&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84865649173&partnerID=8YFLogxK
U2 - 10.1007/s11906-012-0273-8
DO - 10.1007/s11906-012-0273-8
M3 - Article
VL - 14
SP - 333
EP - 338
JO - Current Hypertension Reports
JF - Current Hypertension Reports
SN - 1522-6417
IS - 4
ER -