Total knee prosthesis polyethylene wear reduction by a new metal part finishing method

Antonio Gigante, Valerio Cigna, Sandra Manzotti, Tommaso Villa, Eleonora Salvolini, Monica Mattioli-Belmonte

Research output: Contribution to journalArticlepeer-review


Purpose: The purpose of this study was to assess a new metal component finishing designed to improve total knee prosthesis durability. Wear of ultrahigh molecular-weight polyethylene (UHMWPE), with generation of submicrometer- and micrometer-sized particles, has been associated with osteolysis and artificial joint failure. Wear extent is influenced by several factors, some of which are related to manufacturing. Methods: UHMWPE wear was assessed in metal prosthesis components finished with the Microloy® technology and in traditionally finished components by wear simulation experiments (pin on disk and knee simulator tests) and analysis of wear debris. Results: Microloy®-finished prosthesis showed a 48.5% reduction in UHMWPE total weight loss compared with traditional components (P=0.002). A statistically significant (P

Original languageEnglish
Pages (from-to)99-105
Number of pages7
JournalJournal of Applied Biomaterials and Functional Materials
Issue number2
Publication statusPublished - 2013


  • Knee prosthesis
  • Metal component finishing
  • Scanning electron microscopy (SEM)
  • Simulator
  • Ultrahigh molecular-weight polyethylene (UHMWPE) wear

ASJC Scopus subject areas

  • Biophysics
  • Bioengineering
  • Biomedical Engineering
  • Biomaterials


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