Total submission of lymphadenectomy tissues removed during radical prostatectomy for prostate cancer: Possible clinical significance of large-format histology

Rodolfo Montironi; Marina Scarpelli; Andrea B. Galosi; Antonio Lopez-Beltran; Roberta Mazzucchelli; Francesco Montorsi; Liang Cheng

doi:10.1016/j.humpath.2014.06.023

Total submission of lymphadenectomy tissues removed during radical prostatectomy for prostate cancer: Possible clinical significance of large-format histology

Rodolfo Montironi, Marina Scarpelli, Andrea B. Galosi, Antonio Lopez-Beltran, Roberta Mazzucchelli, Francesco Montorsi, Liang Cheng

IRCCS Ospedale San Raffaele

Research output: Contribution to journal › Article › peer-review

Abstract

Complete submission of lymphadenectomy specimens increases the number of recovered lymph nodes and the detection of metastatic disease. There are advantages with the whole-mount technique over complete sampling with standard cassettes in terms of time needed to sample the tissue, number of blocks to be cut, and slides to be examined. The clinical significance of the approach is that all lymph nodes are identified, including those that are not palpable. In particular, this approach avoids the fact that an individual lymph node is oversampled and counted according to number of pieces obtained by the pathologist, mainly in nodes with considerable size.

Original language	English
Pages (from-to)	2059-2062
Number of pages	4
Journal	Human Pathology
Volume	45
Issue number	10
DOIs	https://doi.org/10.1016/j.humpath.2014.06.023
Publication status	Published - Oct 1 2014

Keywords

Large format histology
Lymphadenectomy tissues
Prostate cancer
Radical prostatectomy
Whole-mount technique

ASJC Scopus subject areas

Pathology and Forensic Medicine
Medicine(all)

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10.1016/j.humpath.2014.06.023

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title = "Total submission of lymphadenectomy tissues removed during radical prostatectomy for prostate cancer: Possible clinical significance of large-format histology",

abstract = "Complete submission of lymphadenectomy specimens increases the number of recovered lymph nodes and the detection of metastatic disease. There are advantages with the whole-mount technique over complete sampling with standard cassettes in terms of time needed to sample the tissue, number of blocks to be cut, and slides to be examined. The clinical significance of the approach is that all lymph nodes are identified, including those that are not palpable. In particular, this approach avoids the fact that an individual lymph node is oversampled and counted according to number of pieces obtained by the pathologist, mainly in nodes with considerable size.",

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T2 - Possible clinical significance of large-format histology

AU - Montironi, Rodolfo

AU - Scarpelli, Marina

AU - Galosi, Andrea B.

AU - Lopez-Beltran, Antonio

AU - Mazzucchelli, Roberta

AU - Montorsi, Francesco

AU - Cheng, Liang

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AB - Complete submission of lymphadenectomy specimens increases the number of recovered lymph nodes and the detection of metastatic disease. There are advantages with the whole-mount technique over complete sampling with standard cassettes in terms of time needed to sample the tissue, number of blocks to be cut, and slides to be examined. The clinical significance of the approach is that all lymph nodes are identified, including those that are not palpable. In particular, this approach avoids the fact that an individual lymph node is oversampled and counted according to number of pieces obtained by the pathologist, mainly in nodes with considerable size.

KW - Large format histology

KW - Lymphadenectomy tissues

KW - Prostate cancer

KW - Radical prostatectomy

KW - Whole-mount technique

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Total submission of lymphadenectomy tissues removed during radical prostatectomy for prostate cancer: Possible clinical significance of large-format histology

Abstract

Keywords

ASJC Scopus subject areas

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