TY - JOUR
T1 - Total submission of lymphadenectomy tissues removed during radical prostatectomy for prostate cancer
T2 - Possible clinical significance of large-format histology
AU - Montironi, Rodolfo
AU - Scarpelli, Marina
AU - Galosi, Andrea B.
AU - Lopez-Beltran, Antonio
AU - Mazzucchelli, Roberta
AU - Montorsi, Francesco
AU - Cheng, Liang
PY - 2014/10/1
Y1 - 2014/10/1
N2 - Complete submission of lymphadenectomy specimens increases the number of recovered lymph nodes and the detection of metastatic disease. There are advantages with the whole-mount technique over complete sampling with standard cassettes in terms of time needed to sample the tissue, number of blocks to be cut, and slides to be examined. The clinical significance of the approach is that all lymph nodes are identified, including those that are not palpable. In particular, this approach avoids the fact that an individual lymph node is oversampled and counted according to number of pieces obtained by the pathologist, mainly in nodes with considerable size.
AB - Complete submission of lymphadenectomy specimens increases the number of recovered lymph nodes and the detection of metastatic disease. There are advantages with the whole-mount technique over complete sampling with standard cassettes in terms of time needed to sample the tissue, number of blocks to be cut, and slides to be examined. The clinical significance of the approach is that all lymph nodes are identified, including those that are not palpable. In particular, this approach avoids the fact that an individual lymph node is oversampled and counted according to number of pieces obtained by the pathologist, mainly in nodes with considerable size.
KW - Large format histology
KW - Lymphadenectomy tissues
KW - Prostate cancer
KW - Radical prostatectomy
KW - Whole-mount technique
UR - http://www.scopus.com/inward/record.url?scp=84908213196&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84908213196&partnerID=8YFLogxK
U2 - 10.1016/j.humpath.2014.06.023
DO - 10.1016/j.humpath.2014.06.023
M3 - Article
C2 - 25149553
AN - SCOPUS:84908213196
VL - 45
SP - 2059
EP - 2062
JO - Human Pathology
JF - Human Pathology
SN - 0046-8177
IS - 10
ER -