TY - JOUR
T1 - Tiroidectomia totale versus emitiroidectomia
T2 - Approccio chirurgico al carcinoma papillare della tiroide T1-T2
AU - Di Filippo, Luigi
AU - Giugliano, Gioacchino
AU - Tagliabue, Marta
AU - Gandini, Sara
AU - Sileo, Federica
AU - Allora, Agnese
AU - Grosso, Enrica
AU - Proh, Michele
AU - Basso, Veronica
AU - Scaglione, Donatella
AU - Manzoni, Marco Federico
AU - Ansarin, Mohssen
N1 - Publisher Copyright:
© Società Italiana di Otorinolaringoiatria e Chirurgia Cervico-Facciale.
Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2020/8
Y1 - 2020/8
N2 - The incidence of papillary thyroid carcinoma, which accounts for 80-90% of all thyroid cancers, has recently been increasing. The current study aimed to compare the oncological and functional outcomes of total thyroidectomy (TT) and thyroid lobectomy (TL). To this end, a retrospective single-centre cohort study involving a tertiary care institution was conducted. Data regarding demographics, clinicopathology and postoperative complications from 586 patients with papillary thyroid cancer treated in a single institution were collected. Cox proportional-hazards models were utilised to determine differences in outcomes stratified according to propensity score. Our data suggested no significant difference in the risk for locoregional recurrence or distant metastasis between TL and TT among patients with pT1-2 pN0 papillary carcinoma. TT plays an important role in improving prognosis among patients with metastatic lymph nodes in the central neck compartment (pN1a) (p = 0.001). Moreover, TT had significantly higher rates of postoperative hypocalcaemia and recurrent laryngeal nerve paralysis compared to TL (p < 0.001 and p = 0.02, respectively).
AB - The incidence of papillary thyroid carcinoma, which accounts for 80-90% of all thyroid cancers, has recently been increasing. The current study aimed to compare the oncological and functional outcomes of total thyroidectomy (TT) and thyroid lobectomy (TL). To this end, a retrospective single-centre cohort study involving a tertiary care institution was conducted. Data regarding demographics, clinicopathology and postoperative complications from 586 patients with papillary thyroid cancer treated in a single institution were collected. Cox proportional-hazards models were utilised to determine differences in outcomes stratified according to propensity score. Our data suggested no significant difference in the risk for locoregional recurrence or distant metastasis between TL and TT among patients with pT1-2 pN0 papillary carcinoma. TT plays an important role in improving prognosis among patients with metastatic lymph nodes in the central neck compartment (pN1a) (p = 0.001). Moreover, TT had significantly higher rates of postoperative hypocalcaemia and recurrent laryngeal nerve paralysis compared to TL (p < 0.001 and p = 0.02, respectively).
KW - Hypocalcaemia
KW - Papillary thyroid cancer
KW - Recurrent laryngeal nerve paralysis
KW - Thyroid lobectomy
KW - Total thyroidectomy
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U2 - 10.14639/0392-100X-N0608
DO - 10.14639/0392-100X-N0608
M3 - Articolo
C2 - 33100336
AN - SCOPUS:85092219961
VL - 40
SP - 254
EP - 261
JO - Acta Otorhinolaryngologica Italica
JF - Acta Otorhinolaryngologica Italica
SN - 0392-100X
IS - 4
ER -