Oftalmoplegia completa transitoria in un caso di sclerosi multipla

Translated title of the contribution: Total transitory ophtalmoplegia in a case of multiple sclerosis

Raffaele Paolo Cioffi, Tatiana Koudriavtseva, Loredana Bove, Andrea Cobianchi, Anna Rosa Casini, Antonio Salerno, Mauro Brogi

Research output: Contribution to journalArticlepeer-review


The case of a young woman admitted to our Hospital for a complete paralysis of voluntary ocular movements is reported. MR of the brain showed an hyperintense area in T2-weighted scans located in the floor of the fourth ventricle, with enhancement after c.m. and others periventricular lesions in the white matter of the brain, suggesting the diagnosis of multiple sclerosis. After a strong therapy with corticosteroids, a progressive recovery of the ocular voluntary movements was observed. We conclude that acute vertical and horizontal ophtalmoplegia can be secondary to a single brainstem lesion at the level of the floor of the fourth ventricle with probable involvement of the pontine paramedian reticular formation (PPRF). Our data suggest that PPRF exerts a key role also in the control of mesencephalic rostro-medial nuclei involved in generation of vertical voluntary ocular movement.

Translated title of the contributionTotal transitory ophtalmoplegia in a case of multiple sclerosis
Original languageItalian
Pages (from-to)25-29
Number of pages5
JournalRivista di Neurobiologia
Issue number1-2
Publication statusPublished - 2002

ASJC Scopus subject areas

  • Neuroscience(all)


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