Toward a B-cell signature of tolerance

Daniela Cugini; Marina Noris

doi:10.1038/ki.2010.159

Toward a B-cell signature of tolerance

Daniela Cugini, Marina Noris

Istituto di Ricerche Farmacologiche "Mario Negri"

Research output: Contribution to journal › Article › peer-review

Abstract

Operational tolerance is a rare and still unexplained phenomenon in organ transplantation. Pallier et al. analyzed the peripheral B-cell compartment of 12 renal transplant patients with drug-free long-term graft function and found a peculiar blood B-cell phenotype, with an expansion of memory activated B cells and increased expression of inhibitory molecules, suggesting a role of B cells in maintaining graft tolerance.

Original language	English
Pages (from-to)	435-437
Number of pages	3
Journal	Kidney International
Volume	78
Issue number	5
DOIs	https://doi.org/10.1038/ki.2010.159
Publication status	Published - Sep 2010

ASJC Scopus subject areas

Nephrology

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