Toward a B-cell signature of tolerance

Daniela Cugini, Marina Noris

Research output: Contribution to journalArticlepeer-review


Operational tolerance is a rare and still unexplained phenomenon in organ transplantation. Pallier et al. analyzed the peripheral B-cell compartment of 12 renal transplant patients with drug-free long-term graft function and found a peculiar blood B-cell phenotype, with an expansion of memory activated B cells and increased expression of inhibitory molecules, suggesting a role of B cells in maintaining graft tolerance.

Original languageEnglish
Pages (from-to)435-437
Number of pages3
JournalKidney International
Issue number5
Publication statusPublished - Sep 2010

ASJC Scopus subject areas

  • Nephrology


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