Toxoplasma cyst detection in Piringer-Kuchinka lymphadenitis. Report of two cases and literature review

Luca Ventura, Magda Zanelli, Maurizio Zizzo, Francesca Sanguedolce, Giovanni Martino, Carolina Castro Ruiz, Valerio Annessi, Stefano Ascani

Research output: Contribution to journalReview articlepeer-review

Abstract

The diagnosis of acute toxoplasmic lymphadenitis is traditionally based on the combination of lymph node excisional biopsy with specific tests. The classic triad (marked follicular hyperplasia, small irregular clusters of epithelioid histiocytes in germinal centers, and sinusoidal distension by monocytoid B lymphocytes) is considered diagnostic of the so-called Piringer-Kuchinka lymphadenitis. Toxoplasma gondii organisms have been exceptionally disclosed in such histopathological setting, establishing the diagnosis of toxoplasmic lymphadenitis. Two cases of Piringer-Kuchinka lymphadenitis with toxoplasma cyst demonstration are reported, along with a complete review of the literature.

Original languageEnglish
Pages (from-to)126-130
Number of pages5
JournalPathologica
Volume113
Issue number2
DOIs
Publication statusPublished - Apr 2021

Keywords

  • Bradyzoites
  • Follicular hyperplasia
  • Toxoplasma cyst
  • Toxoplasma gondii
  • Toxoplasmic lymphadenitis

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

Fingerprint

Dive into the research topics of 'Toxoplasma cyst detection in Piringer-Kuchinka lymphadenitis. Report of two cases and literature review'. Together they form a unique fingerprint.

Cite this