TY - JOUR
T1 - Toxoplasma cyst detection in Piringer-Kuchinka lymphadenitis. Report of two cases and literature review
AU - Ventura, Luca
AU - Zanelli, Magda
AU - Zizzo, Maurizio
AU - Sanguedolce, Francesca
AU - Martino, Giovanni
AU - Ruiz, Carolina Castro
AU - Annessi, Valerio
AU - Ascani, Stefano
N1 - Publisher Copyright:
© 2021 Pacini Editore S.p.A.. All rights reserved.
PY - 2021/4
Y1 - 2021/4
N2 - The diagnosis of acute toxoplasmic lymphadenitis is traditionally based on the combination of lymph node excisional biopsy with specific tests. The classic triad (marked follicular hyperplasia, small irregular clusters of epithelioid histiocytes in germinal centers, and sinusoidal distension by monocytoid B lymphocytes) is considered diagnostic of the so-called Piringer-Kuchinka lymphadenitis. Toxoplasma gondii organisms have been exceptionally disclosed in such histopathological setting, establishing the diagnosis of toxoplasmic lymphadenitis. Two cases of Piringer-Kuchinka lymphadenitis with toxoplasma cyst demonstration are reported, along with a complete review of the literature.
AB - The diagnosis of acute toxoplasmic lymphadenitis is traditionally based on the combination of lymph node excisional biopsy with specific tests. The classic triad (marked follicular hyperplasia, small irregular clusters of epithelioid histiocytes in germinal centers, and sinusoidal distension by monocytoid B lymphocytes) is considered diagnostic of the so-called Piringer-Kuchinka lymphadenitis. Toxoplasma gondii organisms have been exceptionally disclosed in such histopathological setting, establishing the diagnosis of toxoplasmic lymphadenitis. Two cases of Piringer-Kuchinka lymphadenitis with toxoplasma cyst demonstration are reported, along with a complete review of the literature.
KW - Bradyzoites
KW - Follicular hyperplasia
KW - Toxoplasma cyst
KW - Toxoplasma gondii
KW - Toxoplasmic lymphadenitis
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U2 - 10.32074/1591-951X-139
DO - 10.32074/1591-951X-139
M3 - Review article
C2 - 34042094
AN - SCOPUS:85106903745
VL - 113
SP - 126
EP - 130
JO - Pathologica
JF - Pathologica
SN - 0031-2983
IS - 2
ER -