TY - JOUR
T1 - Tracheal compression by aberrant innominate artery
T2 - clinical presentations in infants and children, indications for surgical correction by aortopexy, and short- and long-term outcome
AU - Gardella, Chiara
AU - Girosi, Donata
AU - Rossi, Giovanni A.
AU - Silvestri, Michela
AU - Tomà, Paolo
AU - Bava, Gianlauro
AU - Sacco, Oliviero
PY - 2010/3
Y1 - 2010/3
N2 - Background: Aberrant innominate artery (AIA) may cause various degrees of tracheal compression (TC). Purpose: The aim of this study is to define the clinical manifestations of AIA-induced TC and outcome after aortopexy in infants and older children. Methods: Children with significant AIA-induced TC were evaluated, and information after surgery or conservative management was obtained by telephonic interview after 1 to 4 years since discharge. Results: Overall, 15 infants (mean age, 8 months; group A) and 13 older children (mean age, 56 months; group B) were evaluated. Although median age at onset of symptoms was comparable in the 2 groups, mean delay to diagnosis was higher in group B (P <.0001). Analysis of the most prevalent symptoms showed that reflex apneas were more frequent in group A (P = .02), whereas chronic "intractable" cough was more frequent in group B (P <.001). Because of the type and severity of symptoms and the degree of TC, 16 patients underwent aortopexy. Follow-up evaluation showed, in all but 1 patient, a significant improvement in symptoms and quality of life, measured by a modified Visick score. Conclusions: Aberrant innominate artery-TC leads to a variety of respiratory disorders, with a difference in prevalence between infants and older children. When choice of treatment is based on clinical presentation and degree of TC, a good clinical outcome may be obtained also in children in whom aortopexy is indicated, that is, those presenting initially with more severe symptoms.
AB - Background: Aberrant innominate artery (AIA) may cause various degrees of tracheal compression (TC). Purpose: The aim of this study is to define the clinical manifestations of AIA-induced TC and outcome after aortopexy in infants and older children. Methods: Children with significant AIA-induced TC were evaluated, and information after surgery or conservative management was obtained by telephonic interview after 1 to 4 years since discharge. Results: Overall, 15 infants (mean age, 8 months; group A) and 13 older children (mean age, 56 months; group B) were evaluated. Although median age at onset of symptoms was comparable in the 2 groups, mean delay to diagnosis was higher in group B (P <.0001). Analysis of the most prevalent symptoms showed that reflex apneas were more frequent in group A (P = .02), whereas chronic "intractable" cough was more frequent in group B (P <.001). Because of the type and severity of symptoms and the degree of TC, 16 patients underwent aortopexy. Follow-up evaluation showed, in all but 1 patient, a significant improvement in symptoms and quality of life, measured by a modified Visick score. Conclusions: Aberrant innominate artery-TC leads to a variety of respiratory disorders, with a difference in prevalence between infants and older children. When choice of treatment is based on clinical presentation and degree of TC, a good clinical outcome may be obtained also in children in whom aortopexy is indicated, that is, those presenting initially with more severe symptoms.
KW - Aortopexy
KW - Childhood
KW - Innominate artery
KW - Tracheal compression
UR - http://www.scopus.com/inward/record.url?scp=77649221977&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=77649221977&partnerID=8YFLogxK
U2 - 10.1016/j.jpedsurg.2009.04.028
DO - 10.1016/j.jpedsurg.2009.04.028
M3 - Article
C2 - 20223321
AN - SCOPUS:77649221977
VL - 45
SP - 564
EP - 573
JO - Journal of Pediatric Surgery
JF - Journal of Pediatric Surgery
SN - 0022-3468
IS - 3
ER -