Transcatheter aortic valve implantation in failed bioprosthetic surgical valves

Danny Dvir, John G. Webb, Sabine Bleiziffer, Miralem Pasic, Ron Waksman, Susheel Kodali, Marco Barbanti, Azeem Latib, Ulrich Schaefer, Josep Rodés-Cabau, Hendrik Treede, Nicolo Piazza, David Hildick-Smith, Dominique Himbert, Thomas Walther, Christian Hengstenberg, Henrik Nissen, Raffi Bekeredjian, Patrizia Presbitero, Enrico FerrariAmit Segev, Arend De Weger, Stephan Windecker, Neil E. Moat, Massimo Napodano, Manuel Wilbring, Alfredo G. Cerillo, Stephen Brecker, Didier Tchetche, Thierry Lefèvre, Federico De Marco, Claudia Fiorina, Anna Sonia Petronio, Rui C. Teles, Luca Testa, Jean Claude Laborde, Martin B. Leon, Ran Kornowski

Research output: Contribution to journalArticlepeer-review


IMPORTANCE: Owing to a considerable shift toward bioprosthesis implantation rather than mechanical valves, it is expected that patients will increasingly present with degenerated bioprostheses in the next few years. Transcatheter aortic valve-in-valve implantation is a less invasive approach for patients with structural valve deterioration; however, a comprehensive evaluation of survival after the procedure has not yet been performed. OBJECTIVE: To determine the survival of patients after transcatheter valve-in-valve implantation inside failed surgical bioprosthetic valves. DESIGN, SETTING, AND PARTICIPANTS: Correlates for survival were evaluated using a multinational valve-in-valve registry that included 459 patients with degenerated bioprosthetic valves undergoing valve-in-valve implantation between 2007 and May 2013 in 55 centers (mean age, 77.6 [SD, 9.8] years; 56% men; median Society of Thoracic Surgeons mortality prediction score, 9.8% [interquartile range, 7.7%-16%]). Surgical valves were classified as small (≤21 mm; 29.7%), intermediate (>21 and

Original languageEnglish
Pages (from-to)162-170
Number of pages9
JournalJournal of the American Medical Association
Issue number2
Publication statusPublished - 2014

ASJC Scopus subject areas

  • Medicine(all)


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