Transcatheter aortic valve implantation in patients with severe left ventricular dysfunction: Immediate and mid-term results, a multicenter study

Chiara Fraccaro; Rasha Al-Lamee; Giuseppe Tarantini; Francesco Maisano; Massimo Napodano; Matteo Montorfano; Anna Chiara Frigo; Sabino Iliceto; Gino Gerosa; Giambattista Isabella; Antonio Colombo

doi:10.1161/CIRCINTERVENTIONS.111.964213

Transcatheter aortic valve implantation in patients with severe left ventricular dysfunction: Immediate and mid-term results, a multicenter study

Chiara Fraccaro, Rasha Al-Lamee, Giuseppe Tarantini, Francesco Maisano, Massimo Napodano, Matteo Montorfano, Anna Chiara Frigo, Sabino Iliceto, Gino Gerosa, Giambattista Isabella, Antonio Colombo

IRCCS Ospedale San Raffaele

Research output: Contribution to journal › Article › peer-review

Abstract

Background-Few data exist about transcatheter aortic valve implantation (TAVI) in patients with low ejection fraction. The aim of the study was to analyze safety, feasibility, and efficacy of TAVI in patients with severe left ventricular dysfunction. Methods and Results-The study sample (384 patients) was divided into 2 groups: group A (50 patients) with left ventricular ejection fraction (LVEF) ≤35%, and group B (334 patients) with LVEF >35%. Clinical, anatomic, and hemodynamic variables, as well as procedural results and follow-up outcomes, were compared between the groups. Procedural success was reached in 88%, with no significant difference between the groups. The incidence of periprosthetic leak >2+/4 after TAVI was higher in group A. All other complications were similar between the 2 groups. Group A showed a significant and early improvement in LVEF (from 27.7±6.0 -35.2±11.1 after TAVI; P

Original language	English
Pages (from-to)	253-260
Number of pages	8
Journal	Circulation: Cardiovascular Interventions
Volume	5
Issue number	2
DOIs	https://doi.org/10.1161/CIRCINTERVENTIONS.111.964213
Publication status	Published - Apr 2012

Keywords

30-day mortality
Aortic stenosis
Left ventricular dysfunction
Left ventricular ejection fraction
Transcatheter aortic valve implantation

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

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Fraccaro, C., Al-Lamee, R., Tarantini, G., Maisano, F., Napodano, M., Montorfano, M., Frigo, A. C., Iliceto, S., Gerosa, G., Isabella, G., & Colombo, A. (2012). Transcatheter aortic valve implantation in patients with severe left ventricular dysfunction: Immediate and mid-term results, a multicenter study. Circulation: Cardiovascular Interventions, 5(2), 253-260. https://doi.org/10.1161/CIRCINTERVENTIONS.111.964213

Transcatheter aortic valve implantation in patients with severe left ventricular dysfunction : Immediate and mid-term results, a multicenter study. / Fraccaro, Chiara; Al-Lamee, Rasha; Tarantini, Giuseppe; Maisano, Francesco; Napodano, Massimo; Montorfano, Matteo; Frigo, Anna Chiara; Iliceto, Sabino; Gerosa, Gino; Isabella, Giambattista; Colombo, Antonio.

In: Circulation: Cardiovascular Interventions, Vol. 5, No. 2, 04.2012, p. 253-260.

Research output: Contribution to journal › Article › peer-review

Fraccaro, C, Al-Lamee, R, Tarantini, G, Maisano, F, Napodano, M, Montorfano, M, Frigo, AC, Iliceto, S, Gerosa, G, Isabella, G & Colombo, A 2012, 'Transcatheter aortic valve implantation in patients with severe left ventricular dysfunction: Immediate and mid-term results, a multicenter study', Circulation: Cardiovascular Interventions, vol. 5, no. 2, pp. 253-260. https://doi.org/10.1161/CIRCINTERVENTIONS.111.964213

Fraccaro, Chiara ; Al-Lamee, Rasha ; Tarantini, Giuseppe ; Maisano, Francesco ; Napodano, Massimo ; Montorfano, Matteo ; Frigo, Anna Chiara ; Iliceto, Sabino ; Gerosa, Gino ; Isabella, Giambattista ; Colombo, Antonio. / Transcatheter aortic valve implantation in patients with severe left ventricular dysfunction : Immediate and mid-term results, a multicenter study. In: Circulation: Cardiovascular Interventions. 2012 ; Vol. 5, No. 2. pp. 253-260.

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