Transcatheter aortic valve implantation in patients with severe left ventricular dysfunction: Immediate and mid-term results, a multicenter study

Chiara Fraccaro, Rasha Al-Lamee, Giuseppe Tarantini, Francesco Maisano, Massimo Napodano, Matteo Montorfano, Anna Chiara Frigo, Sabino Iliceto, Gino Gerosa, Giambattista Isabella, Antonio Colombo

Research output: Contribution to journalArticlepeer-review

Abstract

Background-Few data exist about transcatheter aortic valve implantation (TAVI) in patients with low ejection fraction. The aim of the study was to analyze safety, feasibility, and efficacy of TAVI in patients with severe left ventricular dysfunction. Methods and Results-The study sample (384 patients) was divided into 2 groups: group A (50 patients) with left ventricular ejection fraction (LVEF) ≤35%, and group B (334 patients) with LVEF >35%. Clinical, anatomic, and hemodynamic variables, as well as procedural results and follow-up outcomes, were compared between the groups. Procedural success was reached in 88%, with no significant difference between the groups. The incidence of periprosthetic leak >2+/4 after TAVI was higher in group A. All other complications were similar between the 2 groups. Group A showed a significant and early improvement in LVEF (from 27.7±6.0 -35.2±11.1 after TAVI; P

Original languageEnglish
Pages (from-to)253-260
Number of pages8
JournalCirculation: Cardiovascular Interventions
Volume5
Issue number2
DOIs
Publication statusPublished - Apr 2012

Keywords

  • 30-day mortality
  • Aortic stenosis
  • Left ventricular dysfunction
  • Left ventricular ejection fraction
  • Transcatheter aortic valve implantation

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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