TY - JOUR
T1 - Transcatheter aortic valve implantation in patients with severe left ventricular dysfunction
T2 - Immediate and mid-term results, a multicenter study
AU - Fraccaro, Chiara
AU - Al-Lamee, Rasha
AU - Tarantini, Giuseppe
AU - Maisano, Francesco
AU - Napodano, Massimo
AU - Montorfano, Matteo
AU - Frigo, Anna Chiara
AU - Iliceto, Sabino
AU - Gerosa, Gino
AU - Isabella, Giambattista
AU - Colombo, Antonio
PY - 2012/4
Y1 - 2012/4
N2 - Background-Few data exist about transcatheter aortic valve implantation (TAVI) in patients with low ejection fraction. The aim of the study was to analyze safety, feasibility, and efficacy of TAVI in patients with severe left ventricular dysfunction. Methods and Results-The study sample (384 patients) was divided into 2 groups: group A (50 patients) with left ventricular ejection fraction (LVEF) ≤35%, and group B (334 patients) with LVEF >35%. Clinical, anatomic, and hemodynamic variables, as well as procedural results and follow-up outcomes, were compared between the groups. Procedural success was reached in 88%, with no significant difference between the groups. The incidence of periprosthetic leak >2+/4 after TAVI was higher in group A. All other complications were similar between the 2 groups. Group A showed a significant and early improvement in LVEF (from 27.7±6.0 -35.2±11.1 after TAVI; P
AB - Background-Few data exist about transcatheter aortic valve implantation (TAVI) in patients with low ejection fraction. The aim of the study was to analyze safety, feasibility, and efficacy of TAVI in patients with severe left ventricular dysfunction. Methods and Results-The study sample (384 patients) was divided into 2 groups: group A (50 patients) with left ventricular ejection fraction (LVEF) ≤35%, and group B (334 patients) with LVEF >35%. Clinical, anatomic, and hemodynamic variables, as well as procedural results and follow-up outcomes, were compared between the groups. Procedural success was reached in 88%, with no significant difference between the groups. The incidence of periprosthetic leak >2+/4 after TAVI was higher in group A. All other complications were similar between the 2 groups. Group A showed a significant and early improvement in LVEF (from 27.7±6.0 -35.2±11.1 after TAVI; P
KW - 30-day mortality
KW - Aortic stenosis
KW - Left ventricular dysfunction
KW - Left ventricular ejection fraction
KW - Transcatheter aortic valve implantation
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U2 - 10.1161/CIRCINTERVENTIONS.111.964213
DO - 10.1161/CIRCINTERVENTIONS.111.964213
M3 - Article
C2 - 22496081
AN - SCOPUS:84860818415
VL - 5
SP - 253
EP - 260
JO - Circulation: Cardiovascular Interventions
JF - Circulation: Cardiovascular Interventions
SN - 1941-7640
IS - 2
ER -