Abstract
BACKGROUND AND PURPOSE: Cerebral vasomotor reserve (VMR) is the capability of cerebral arterioles to change their diameter in response to various stimuli, such hypercapnia. Changes of VMR due to transcranial direct current stimulation (tDCS) have been poorly studied. METHODS: Twenty-five healthy subjects underwent anodal/cathodal and sham tDCS on right primary motor area. Before and after tDCS, we assessed VMR by Transcranial Color-Coded Sonography (TCCS) calculating trought Breath Holding Index (BHI) and Heart Rate Variability (HRV), in particular after Valsalva manouver. RESULTS: A-tDCS decreased VMR and BHI (p <0.05), whereas C-tDCS increased VMR, and BHI (p <0.05); Sham doesn't provide statistically significant of both VMR, BHI and HRV (p > 0.05). CONCLUSIONS: Our study confirms that tDCS induces a modification of bilateral VMR with a polarity-specific effect; based on this bilateral MFV and BHI modifications, we can speculate an involvement of the SNS in the VMR regulation.
| Original language | English |
|---|---|
| Pages (from-to) | 571-574 |
| Number of pages | 4 |
| Journal | Journal of Neuroimaging |
| Volume | 25 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - Jul 1 2015 |
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Keywords
- Carotid stenosis
- Heart rate variability
- TDCS
- Vasomotor reserve
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging
- Clinical Neurology
Cite this
Transcranial Direct Current Stimulation and Cerebral Vasomotor Reserve : A Study in Healthy Subjects. / Giorli, Elisa; Tognazzi, Silvia; Briscese, Lucia; Bocci, Tommaso; Mazzatenta, Andrea; Priori, Alberto; Orlandi, Giovanni; Del Sette, Massimo; Sartucci, Ferdinando.
In: Journal of Neuroimaging, Vol. 25, No. 4, 01.07.2015, p. 571-574.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Transcranial Direct Current Stimulation and Cerebral Vasomotor Reserve
T2 - A Study in Healthy Subjects
AU - Giorli, Elisa
AU - Tognazzi, Silvia
AU - Briscese, Lucia
AU - Bocci, Tommaso
AU - Mazzatenta, Andrea
AU - Priori, Alberto
AU - Orlandi, Giovanni
AU - Del Sette, Massimo
AU - Sartucci, Ferdinando
PY - 2015/7/1
Y1 - 2015/7/1
N2 - BACKGROUND AND PURPOSE: Cerebral vasomotor reserve (VMR) is the capability of cerebral arterioles to change their diameter in response to various stimuli, such hypercapnia. Changes of VMR due to transcranial direct current stimulation (tDCS) have been poorly studied. METHODS: Twenty-five healthy subjects underwent anodal/cathodal and sham tDCS on right primary motor area. Before and after tDCS, we assessed VMR by Transcranial Color-Coded Sonography (TCCS) calculating trought Breath Holding Index (BHI) and Heart Rate Variability (HRV), in particular after Valsalva manouver. RESULTS: A-tDCS decreased VMR and BHI (p <0.05), whereas C-tDCS increased VMR, and BHI (p <0.05); Sham doesn't provide statistically significant of both VMR, BHI and HRV (p > 0.05). CONCLUSIONS: Our study confirms that tDCS induces a modification of bilateral VMR with a polarity-specific effect; based on this bilateral MFV and BHI modifications, we can speculate an involvement of the SNS in the VMR regulation.
AB - BACKGROUND AND PURPOSE: Cerebral vasomotor reserve (VMR) is the capability of cerebral arterioles to change their diameter in response to various stimuli, such hypercapnia. Changes of VMR due to transcranial direct current stimulation (tDCS) have been poorly studied. METHODS: Twenty-five healthy subjects underwent anodal/cathodal and sham tDCS on right primary motor area. Before and after tDCS, we assessed VMR by Transcranial Color-Coded Sonography (TCCS) calculating trought Breath Holding Index (BHI) and Heart Rate Variability (HRV), in particular after Valsalva manouver. RESULTS: A-tDCS decreased VMR and BHI (p <0.05), whereas C-tDCS increased VMR, and BHI (p <0.05); Sham doesn't provide statistically significant of both VMR, BHI and HRV (p > 0.05). CONCLUSIONS: Our study confirms that tDCS induces a modification of bilateral VMR with a polarity-specific effect; based on this bilateral MFV and BHI modifications, we can speculate an involvement of the SNS in the VMR regulation.
KW - Carotid stenosis
KW - Heart rate variability
KW - TDCS
KW - Vasomotor reserve
UR - http://www.scopus.com/inward/record.url?scp=84937036125&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84937036125&partnerID=8YFLogxK
U2 - 10.1111/jon.12162
DO - 10.1111/jon.12162
M3 - Article
AN - SCOPUS:84937036125
VL - 25
SP - 571
EP - 574
JO - Journal of Neuroimaging
JF - Journal of Neuroimaging
SN - 1051-2284
IS - 4
ER -