Transcranial Doppler assessment of cerebrovascular reactivity in symptomatic and asymptomatic severe carotid stenosis

Mauro Silvestrini, Elio Troisi, Maria Matteis, Letizia M. Cupini, Carlo Caltagirone

Research output: Contribution to journalArticle

Abstract

Background and Purpose: Some studies have suggested a link between impaired cerebral hemodynamics and stroke in patients with carotid stenosis. The aim of this study was to assess the effects of severe carotid stenosis on cerebrovascular reactivity and the possible changes after endarterectomy. Methods: Using bilateral transcranial Doppler ultrasound, we studied the changes of flow velocity after hypercapnia in the middle cerebral arteries of 10 control subjects and 24 patients (13 symptomatic and 11 asymptomatic) with unilateral severe carotid stenosis before and after endarterectomy. Cerebrovascular reactivity was evaluated with the breath-holding index (BHI). Results: Before endarterectomy, BHI (recall value±SD) was significantly lower (P

Original languageEnglish
Pages (from-to)1970-1973
Number of pages4
JournalStroke
Volume27
Issue number11
Publication statusPublished - Nov 1996

Keywords

  • carotid stenosis
  • vasomotor reactivity

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Neuroscience(all)

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