Transcranial Doppler sonography in familial hemiplegic migraine.

F. Pierelli, F. Pauri, L. M. Cupini, G. Fiermonte, P. A. Rizzo

Research output: Contribution to journalArticlepeer-review


A patient affected by familial hemiplegic migraine underwent Transcranial Doppler Sonography twice: the first during a spontaneous attack with right hemiparesis and aphasia, the second during a headache-free period. During the attack the following haemodynamic changes were seen: (a) bilateral increase in the middle cerebral artery and anterior cerebral artery blood flow velocities (this increase was more pronounced on the left side), (b) decreased systo-diastolic ratio and pulsatility index on the right side, (c) increased systo-diastolic ratio and pulsatility index on the left side. Our results indicate that during the attack in this familial hemiplegic migraine patient a diffuse vasoconstriction of the basal cerebral arteries developed. Moreover, Transcranial Doppler Sonography data suggest that a prolonged vasoconstriction of the peripheral arterioles could play a role in determining the neurological symptoms in this syndrome.

Original languageEnglish
Pages (from-to)29-31
Number of pages3
Issue number1
Publication statusPublished - Feb 1991

ASJC Scopus subject areas

  • Clinical Neurology


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