Transcranial Doppler (TCD) after nitroglycerin in migraine without aura

E. M. Zanette, A. Agnoli, R. Cerbo, F. Chiarotti, C. Roberti, M. G. Buzzi, C. Fieschi

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Abstract

Nitroglycerin, a vasodilating agent, was administered sublingually in migraine without aura patients and in healthy volunteers. Systolic, diastolic and time-mean flow velocity and pulsatility index, were measured by transcranial Doppler sonography in the major intracranial arteries before and after nitroglycerin administration. Following nitroglycerin administration, a significant decrease in systolic and time-mean velocity and pulsatility index was observed in migraine patients, whereas in control subjects only time-mean velocity decreased significantly. Based on those findings we hypothesize a more marked responsiveness to nitroglycerin in migraine patients as compared to healthy subjects.

Original languageEnglish
Pages (from-to)596-598
Number of pages3
JournalHeadache
Volume31
Issue number9
Publication statusPublished - 1991

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ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

Cite this

Zanette, E. M., Agnoli, A., Cerbo, R., Chiarotti, F., Roberti, C., Buzzi, M. G., & Fieschi, C. (1991). Transcranial Doppler (TCD) after nitroglycerin in migraine without aura. Headache, 31(9), 596-598.