Transcranial magnetic stimulation investigations of reaching and grasping movements

Giacomo Koch, John C. Rothwell

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Citations (Scopus)

Abstract

Transcranial magnetic stimulation (TMS) has emerged as a suitable technique to investigate the network of cortical areas involved in human grasp/reach movements. Applied over the primary motor cortex (M1), TMS reveals the pattern of activation of different muscles during complex reaching-to-grasp tasks. Repetitive TMS (rTMS) used to induce “virtual lesions” of other cortical areas has allowed investigation of other cortical structures such as the ventral premotor cortex (PMv), dorsal premotor cortex (PMd) and the anterior intraparietal sulcus (aIPS). Each of these appears to contribute to specific aspects of reaching, grasping and lifting objects. Finally, twin-coil TMS studies can illustrate the time course of operation of parallel intracortical circuits that mediate functional connectivity between the PMd, PMv, the posterior parietal cortex and the primary motor cortices.: Introduction: The ease with which we can make reach-to-grasp movements conceals a good deal of the underlying complexity of the task. Thus, the target of the reach must be located in space; a decision must be made about the most appropriate type and orientation of grasp according to the weight and shape of the object; and the timing of the reaching movement of the arm must be synchronized with the opening of the hand so that the object can be grasped as effectively and quickly as possible (for a review see Castiello, 2005; see also Chapters 2 and 10).

Original languageEnglish
Title of host publicationSensorimotor Control of Grasping: Physiology and Pathophysiology
PublisherCambridge University Press
Pages72-83
Number of pages12
ISBN (Print)9780511581267, 9780521881579
DOIs
Publication statusPublished - Jan 1 2009

Fingerprint

Transcranial Magnetic Stimulation
Motor Cortex
Hand Strength
Parietal Lobe
Arm
Hand
Weights and Measures
Muscles

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Koch, G., & Rothwell, J. C. (2009). Transcranial magnetic stimulation investigations of reaching and grasping movements. In Sensorimotor Control of Grasping: Physiology and Pathophysiology (pp. 72-83). Cambridge University Press. https://doi.org/10.1017/CBO9780511581267.007

Transcranial magnetic stimulation investigations of reaching and grasping movements. / Koch, Giacomo; Rothwell, John C.

Sensorimotor Control of Grasping: Physiology and Pathophysiology. Cambridge University Press, 2009. p. 72-83.

Research output: Chapter in Book/Report/Conference proceedingChapter

Koch, G & Rothwell, JC 2009, Transcranial magnetic stimulation investigations of reaching and grasping movements. in Sensorimotor Control of Grasping: Physiology and Pathophysiology. Cambridge University Press, pp. 72-83. https://doi.org/10.1017/CBO9780511581267.007
Koch G, Rothwell JC. Transcranial magnetic stimulation investigations of reaching and grasping movements. In Sensorimotor Control of Grasping: Physiology and Pathophysiology. Cambridge University Press. 2009. p. 72-83 https://doi.org/10.1017/CBO9780511581267.007
Koch, Giacomo ; Rothwell, John C. / Transcranial magnetic stimulation investigations of reaching and grasping movements. Sensorimotor Control of Grasping: Physiology and Pathophysiology. Cambridge University Press, 2009. pp. 72-83
@inbook{bb5f7a3b408a49bcb1d622b5bf6ddac4,
title = "Transcranial magnetic stimulation investigations of reaching and grasping movements",
abstract = "Transcranial magnetic stimulation (TMS) has emerged as a suitable technique to investigate the network of cortical areas involved in human grasp/reach movements. Applied over the primary motor cortex (M1), TMS reveals the pattern of activation of different muscles during complex reaching-to-grasp tasks. Repetitive TMS (rTMS) used to induce “virtual lesions” of other cortical areas has allowed investigation of other cortical structures such as the ventral premotor cortex (PMv), dorsal premotor cortex (PMd) and the anterior intraparietal sulcus (aIPS). Each of these appears to contribute to specific aspects of reaching, grasping and lifting objects. Finally, twin-coil TMS studies can illustrate the time course of operation of parallel intracortical circuits that mediate functional connectivity between the PMd, PMv, the posterior parietal cortex and the primary motor cortices.: Introduction: The ease with which we can make reach-to-grasp movements conceals a good deal of the underlying complexity of the task. Thus, the target of the reach must be located in space; a decision must be made about the most appropriate type and orientation of grasp according to the weight and shape of the object; and the timing of the reaching movement of the arm must be synchronized with the opening of the hand so that the object can be grasped as effectively and quickly as possible (for a review see Castiello, 2005; see also Chapters 2 and 10).",
author = "Giacomo Koch and Rothwell, {John C.}",
year = "2009",
month = "1",
day = "1",
doi = "10.1017/CBO9780511581267.007",
language = "English",
isbn = "9780511581267",
pages = "72--83",
booktitle = "Sensorimotor Control of Grasping: Physiology and Pathophysiology",
publisher = "Cambridge University Press",

}

TY - CHAP

T1 - Transcranial magnetic stimulation investigations of reaching and grasping movements

AU - Koch, Giacomo

AU - Rothwell, John C.

PY - 2009/1/1

Y1 - 2009/1/1

N2 - Transcranial magnetic stimulation (TMS) has emerged as a suitable technique to investigate the network of cortical areas involved in human grasp/reach movements. Applied over the primary motor cortex (M1), TMS reveals the pattern of activation of different muscles during complex reaching-to-grasp tasks. Repetitive TMS (rTMS) used to induce “virtual lesions” of other cortical areas has allowed investigation of other cortical structures such as the ventral premotor cortex (PMv), dorsal premotor cortex (PMd) and the anterior intraparietal sulcus (aIPS). Each of these appears to contribute to specific aspects of reaching, grasping and lifting objects. Finally, twin-coil TMS studies can illustrate the time course of operation of parallel intracortical circuits that mediate functional connectivity between the PMd, PMv, the posterior parietal cortex and the primary motor cortices.: Introduction: The ease with which we can make reach-to-grasp movements conceals a good deal of the underlying complexity of the task. Thus, the target of the reach must be located in space; a decision must be made about the most appropriate type and orientation of grasp according to the weight and shape of the object; and the timing of the reaching movement of the arm must be synchronized with the opening of the hand so that the object can be grasped as effectively and quickly as possible (for a review see Castiello, 2005; see also Chapters 2 and 10).

AB - Transcranial magnetic stimulation (TMS) has emerged as a suitable technique to investigate the network of cortical areas involved in human grasp/reach movements. Applied over the primary motor cortex (M1), TMS reveals the pattern of activation of different muscles during complex reaching-to-grasp tasks. Repetitive TMS (rTMS) used to induce “virtual lesions” of other cortical areas has allowed investigation of other cortical structures such as the ventral premotor cortex (PMv), dorsal premotor cortex (PMd) and the anterior intraparietal sulcus (aIPS). Each of these appears to contribute to specific aspects of reaching, grasping and lifting objects. Finally, twin-coil TMS studies can illustrate the time course of operation of parallel intracortical circuits that mediate functional connectivity between the PMd, PMv, the posterior parietal cortex and the primary motor cortices.: Introduction: The ease with which we can make reach-to-grasp movements conceals a good deal of the underlying complexity of the task. Thus, the target of the reach must be located in space; a decision must be made about the most appropriate type and orientation of grasp according to the weight and shape of the object; and the timing of the reaching movement of the arm must be synchronized with the opening of the hand so that the object can be grasped as effectively and quickly as possible (for a review see Castiello, 2005; see also Chapters 2 and 10).

UR - http://www.scopus.com/inward/record.url?scp=77950529687&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77950529687&partnerID=8YFLogxK

U2 - 10.1017/CBO9780511581267.007

DO - 10.1017/CBO9780511581267.007

M3 - Chapter

AN - SCOPUS:77950529687

SN - 9780511581267

SN - 9780521881579

SP - 72

EP - 83

BT - Sensorimotor Control of Grasping: Physiology and Pathophysiology

PB - Cambridge University Press

ER -