Transcranial magnetic stimulation selectively impairs interhemispheric transfer of visuo-motor information in humans

C. A. Marzi, C. Miniussi, A. Maravita, L. Bertolasi, G. Zanette, J. C. Rothwell, J. N. Sanes

Research output: Contribution to journalArticlepeer-review

Abstract

We investigated the cerebral cortical route by which visual information reaches motor cortex when visual signals are used for manual responses. Subjects responded unimanually to photic stimuli delivered to the hemifield ipsilateral or contralateral to the moving hand. On some trials, trans-cranial magnetic stimulation (TMS) was applied unilaterally over the occiput, with the aim of stimulating extrastriate visual areas and thereby modifying transmission of visual input. In association with the side of a visual stimulus and a motor response, TMS could change inter- or intra-hemispheric transmission needed to convey visual information to motor areas. Reaction time differences following TMS suggested that TMS exerted an inhibitory effect only when visuo-motor information had to be transferred interhemispherically. This result reinforces evidence for an extrastriate pathway of interhemispheric transfer of visuomotor information.

Original languageEnglish
Pages (from-to)435-438
Number of pages4
JournalExperimental Brain Research
Volume118
Issue number3
DOIs
Publication statusPublished - 1998

Keywords

  • Human
  • Interhemispheric transfer
  • Manual response
  • Poffenberger paradigm
  • Simple reaction time
  • Transcranial magnetic stimulation

ASJC Scopus subject areas

  • Neuroscience(all)

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