Transcranial pulse inversion and intermittent imaging ultrasound of brain parenchyma perfusion during constant flow rate venous infusion of Levovist: Differentiation between normal subjects and atherosclerotic patients

F. Calliada, O. Bottineili, M. G. Sommaruga, L. Madonia, D. Coscia, R. Campani

Research output: Contribution to journalArticle


The brain perfusion patterns were examined in normal versus atherosclerotic patients using transcranial pulse inversion and intermittent ultrasound during constant infusion of levovist. The mean signal enhancement postcontrast in healthy volunteers was 25.9% at the basal nuclei and 46.8% at subcortical level as against 22.4% and 38.3%. Thus, the transcranial and intermittent ultrasound of brain parenchyma during constant flow rate venous infusion appears to be a promising technique.

Original languageEnglish
JournalUltrasound in Medicine and Biology
Issue numberSUPPL. 2
Publication statusPublished - 2000


ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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