Transepidermal water loss and skin surface hydration in the non invasive assessment of stratum corneum function

E. Berardesca, H. I. Maibach

Research output: Contribution to journalArticle

Abstract

Transepidermal water loss (TEWL) and water content of the stratum corneum, when measured simultaneously, provide important information regarding skin function. On the basis of the model presented, it is possible to differentiate dry senile skin from dry pathological skin (such as psoriasis, atopic dermatitis, irritant reaction), clinically involved or uninvolved. Pathological dry skin, because of the impaired barrier function is associated with increased TEWL and low corneum water content. Senile skin, on the other hand, shows both, decreased TEWL and stratum corneum water content. It is suggested that with this model it may be possible to differentiate uninvolved pathologic from healthy skin.

Original languageEnglish
Pages (from-to)50-53
Number of pages4
JournalDermatosen in Beruf und Umwelt
Volume38
Issue number2
Publication statusPublished - 1990

ASJC Scopus subject areas

  • Dermatology
  • Public Health, Environmental and Occupational Health

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