Abstract
A diagnostic examination for short stature in a boy with chronic ulcers of the feet due to prolidase deficiency, a rare disorder associated with intractable ulcers of the skin, led to the diagnosis of growth hormone (GH) deficiency. Replacement treatment with r-hGH associated with the topical application of a GH-containing ointment when the boy was 13 years old resulted in complete but transitory heating of the ulcers, which can probably be attributed to the growth-promoting effects of GH on dermal connective tissue.
| Original language | English |
|---|---|
| Pages (from-to) | 227-230 |
| Number of pages | 4 |
| Journal | Pediatric Dermatology |
| Volume | 17 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - May 2000 |
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ASJC Scopus subject areas
- Dermatology
- Pediatrics, Perinatology, and Child Health
Cite this
Transient beneficial effect of GH replacement therapy and topical GH application on skin ulcers in a boy with prolidase deficiency. / Monafo, Virginia; Marseglia, Gian Luigi; Maghnie, Mohamad; Dyne, Katherine M.; Cetta, Giuseppe.
In: Pediatric Dermatology, Vol. 17, No. 3, 05.2000, p. 227-230.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Transient beneficial effect of GH replacement therapy and topical GH application on skin ulcers in a boy with prolidase deficiency
AU - Monafo, Virginia
AU - Marseglia, Gian Luigi
AU - Maghnie, Mohamad
AU - Dyne, Katherine M.
AU - Cetta, Giuseppe
PY - 2000/5
Y1 - 2000/5
N2 - A diagnostic examination for short stature in a boy with chronic ulcers of the feet due to prolidase deficiency, a rare disorder associated with intractable ulcers of the skin, led to the diagnosis of growth hormone (GH) deficiency. Replacement treatment with r-hGH associated with the topical application of a GH-containing ointment when the boy was 13 years old resulted in complete but transitory heating of the ulcers, which can probably be attributed to the growth-promoting effects of GH on dermal connective tissue.
AB - A diagnostic examination for short stature in a boy with chronic ulcers of the feet due to prolidase deficiency, a rare disorder associated with intractable ulcers of the skin, led to the diagnosis of growth hormone (GH) deficiency. Replacement treatment with r-hGH associated with the topical application of a GH-containing ointment when the boy was 13 years old resulted in complete but transitory heating of the ulcers, which can probably be attributed to the growth-promoting effects of GH on dermal connective tissue.
UR - http://www.scopus.com/inward/record.url?scp=0033943005&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0033943005&partnerID=8YFLogxK
U2 - 10.1046/j.1525-1470.2000.01760.x
DO - 10.1046/j.1525-1470.2000.01760.x
M3 - Article
C2 - 10886759
AN - SCOPUS:0033943005
VL - 17
SP - 227
EP - 230
JO - Pediatric Dermatology
JF - Pediatric Dermatology
SN - 0736-8046
IS - 3
ER -