Transient cardiac left ventricular diastolic dysfunction following strenuous exercise

G. Fragasso, A. Palloshi, S. Roi, E. Rossetti, G. Monaco, A. Dolci, A. Margonato, S. Chierchia

Research output: Contribution to journalArticlepeer-review


The long term clinical significance of exercise-induced “cardiac fatigue” has not been clearly addressed. The aim of this study was to assess the effects of repetitive competitive high altitude running on left ventricular performance. Eleven athletes were studied before and after two high altitude races in two consecutive years. On both occasions 12-lead elettrocardiography (ECG) as well as Doppler echocardiography were performed 24 hours before, shortly after (within 30 min) and 24 hours after the end of the race. Measurements included ejection fraction, early (E) and late (A) transmitral inflow velocities, their ratio (E/A) and percent atrial contribution (AC). Similar studies were performed in 11 age- and sex-matched control subjects at baseline and following a maximal exercise test. Ejection fraction remained stable in both. Conversely, Doppler E/A ratio significantly decreased in atletes early after the race from 1.9±0.1 to 1.3±0.1 (p

Original languageEnglish
Pages (from-to)31-35
Number of pages5
JournalSport Sciences for Health
Issue number1
Publication statusPublished - 2004


  • Exertion
  • Fatigue
  • Heart
  • Left ventricular function
  • Sports

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine


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