Transient central sleep apnea runs triggered by disorder of arousal in a child

Lourdes M. DelRosso, Kenneth Martin, Michelle Marcos, Raffaele Ferri

Research output: Contribution to journalArticlepeer-review


We report the case of a 5-year-old girl with frequent nocturnal episodes of disorder of arousal (confusional arousals, sleep terrors, and sleep walking), occurring at the end of periods of slow wave sleep, followed by return to sleep accompanied by the occurrence of periodic breathing with a run of approximately 10 to 20 central events. The duration of the central events and oxyhemoglobin desaturation were both maximum at the beginning of each run and became progressively less prominent with the development of the sequences. Night episodes disappeared with bedtime clonazepam but behavioral problems occurred as a paradoxical response; thus, clonazepam was stopped. Sleep extension and melatonin were then started, which were followed by a reduction of night episode frequency and intensity. This observation appears to be the first report of central sleep apnea sequences triggered by parasomnia and, if confirmed by additional reports, it might be considered to be a possible new classification of “complex parasomnia.”.

Original languageEnglish
Pages (from-to)1075-1078
Number of pages4
JournalJournal of Clinical Sleep Medicine
Issue number6
Publication statusPublished - Jun 15 2018


  • Central apnea
  • Night terrors
  • Parasomnia

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Neurology
  • Clinical Neurology


Dive into the research topics of 'Transient central sleep apnea runs triggered by disorder of arousal in a child'. Together they form a unique fingerprint.

Cite this