TY - JOUR
T1 - Transient elastography assessment of the liver stiffness dynamics during acute hepatitis B
AU - Viganò, Mauro
AU - Massironi, Sara
AU - Lampertico, Pietro
AU - Iavarone, Massimo
AU - Paggi, Silvia
AU - Pozzi, Roberta
AU - Conte, Dario
AU - Colombo, Massimo
PY - 2010/2
Y1 - 2010/2
N2 - Background and aims: The diagnostic accuracy of transient elastography (TE) for assessment of hepatic fibrosis is hampered by several factors, including acute parenchymal injury. Evaluation of liver stiffness (LS) using TE during acute hepatitis B may help to assess chronic hepatitis B patients with flares. Patients and methods: Twelve patients consecutively referred for acute hepatitis B, underwent sequential examinations with TE and laboratory examinations for 24 weeks. Results: On admission, aminotransferase ranged from 487 to 6067 IU/l (median=2590 IU/l) and LS ranged from 7.1 to 57kPa (median=15.6kPa) with nine (75%) patients showing LS greater than 11.9kPa, that is, the predictive cutoff for cirrhosis. LS levels correlated significantly with bilirubin, only (r≤0.58, P
AB - Background and aims: The diagnostic accuracy of transient elastography (TE) for assessment of hepatic fibrosis is hampered by several factors, including acute parenchymal injury. Evaluation of liver stiffness (LS) using TE during acute hepatitis B may help to assess chronic hepatitis B patients with flares. Patients and methods: Twelve patients consecutively referred for acute hepatitis B, underwent sequential examinations with TE and laboratory examinations for 24 weeks. Results: On admission, aminotransferase ranged from 487 to 6067 IU/l (median=2590 IU/l) and LS ranged from 7.1 to 57kPa (median=15.6kPa) with nine (75%) patients showing LS greater than 11.9kPa, that is, the predictive cutoff for cirrhosis. LS levels correlated significantly with bilirubin, only (r≤0.58, P
KW - Acute hepatitis B
KW - FibroScan
KW - Liver stiffness
KW - Transient elastography
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U2 - 10.1097/MEG.0b013e328332d2fa
DO - 10.1097/MEG.0b013e328332d2fa
M3 - Article
C2 - 19855283
AN - SCOPUS:75749117209
VL - 22
SP - 180
EP - 184
JO - European Journal of Gastroenterology and Hepatology
JF - European Journal of Gastroenterology and Hepatology
SN - 0954-691X
IS - 2
ER -