Translational bioinformatics: Challenges and opportunities for case-based reasoning and decision support

Riccardo Bellazzi, Cristiana Larizza, Matteo Gabetta, Giuseppe Milani, Angelo Nuzzo, Valentina Favalli, Eloisa Arbustini

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Translational bioinformatics is bioinformatics applied to human health. Although, up to now, its main focus has been to support molecular medicine research, translational bioinformatics has now the opportunity to design clinical decision support systems based on the combination of -omics data and internet-based knowledge resources. The paper describes the state-of-art of translational bioinformatics highlighting challenges and opportunities for decision support tools and case-based reasoning. It finally reports the design of a new system for supporting diagnosis in dilated cardiomyopathy. The system is able to combine text mining, literature search and case-based retrieval.

Original languageEnglish
Title of host publicationLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Pages1-11
Number of pages11
Volume6176 LNAI
DOIs
Publication statusPublished - 2010
Event18th International Conference on Case-Based Reasoning, ICCBR 2010 - Alessandria, Italy
Duration: Jul 19 2010Jul 22 2010

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume6176 LNAI
ISSN (Print)03029743
ISSN (Electronic)16113349

Other

Other18th International Conference on Case-Based Reasoning, ICCBR 2010
CountryItaly
CityAlessandria
Period7/19/107/22/10

Keywords

  • decision support
  • dilated cardiomyopathy
  • molecular medicine
  • Translational bioinformatics

ASJC Scopus subject areas

  • Computer Science(all)
  • Theoretical Computer Science

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