Translational bioinformatics: Challenges and opportunities for case-based reasoning and decision support

Riccardo Bellazzi; Cristiana Larizza; Matteo Gabetta; Giuseppe Milani; Angelo Nuzzo; Valentina Favalli; Eloisa Arbustini

doi:10.1007/978-3-642-14274-1_1

Translational bioinformatics: Challenges and opportunities for case-based reasoning and decision support

Riccardo Bellazzi, Cristiana Larizza, Matteo Gabetta, Giuseppe Milani, Angelo Nuzzo, Valentina Favalli, Eloisa Arbustini

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

Translational bioinformatics is bioinformatics applied to human health. Although, up to now, its main focus has been to support molecular medicine research, translational bioinformatics has now the opportunity to design clinical decision support systems based on the combination of -omics data and internet-based knowledge resources. The paper describes the state-of-art of translational bioinformatics highlighting challenges and opportunities for decision support tools and case-based reasoning. It finally reports the design of a new system for supporting diagnosis in dilated cardiomyopathy. The system is able to combine text mining, literature search and case-based retrieval.

Original language	English
Title of host publication	Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Pages	1-11
Number of pages	11
Volume	6176 LNAI
DOIs	https://doi.org/10.1007/978-3-642-14274-1_1
Publication status	Published - 2010
Event	18th International Conference on Case-Based Reasoning, ICCBR 2010 - Alessandria, Italy Duration: Jul 19 2010 → Jul 22 2010

Publication series

Name	Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume	6176 LNAI
ISSN (Print)	03029743
ISSN (Electronic)	16113349

Other

Other	18th International Conference on Case-Based Reasoning, ICCBR 2010
Country	Italy
City	Alessandria
Period	7/19/10 → 7/22/10

Keywords

decision support
dilated cardiomyopathy
molecular medicine
Translational bioinformatics

ASJC Scopus subject areas

Computer Science(all)
Theoretical Computer Science

Access to Document

10.1007/978-3-642-14274-1_1

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Cite this

Bellazzi, R., Larizza, C., Gabetta, M., Milani, G., Nuzzo, A., Favalli, V., & Arbustini, E. (2010). Translational bioinformatics: Challenges and opportunities for case-based reasoning and decision support. In Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) (Vol. 6176 LNAI, pp. 1-11). (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); Vol. 6176 LNAI). https://doi.org/10.1007/978-3-642-14274-1_1

Translational bioinformatics : Challenges and opportunities for case-based reasoning and decision support. / Bellazzi, Riccardo; Larizza, Cristiana; Gabetta, Matteo; Milani, Giuseppe; Nuzzo, Angelo; Favalli, Valentina; Arbustini, Eloisa.

Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). Vol. 6176 LNAI 2010. p. 1-11 (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); Vol. 6176 LNAI).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Bellazzi, R, Larizza, C, Gabetta, M, Milani, G, Nuzzo, A, Favalli, V & Arbustini, E 2010, Translational bioinformatics: Challenges and opportunities for case-based reasoning and decision support. in Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). vol. 6176 LNAI, Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), vol. 6176 LNAI, pp. 1-11, 18th International Conference on Case-Based Reasoning, ICCBR 2010, Alessandria, Italy, 7/19/10. https://doi.org/10.1007/978-3-642-14274-1_1

Bellazzi R, Larizza C, Gabetta M, Milani G, Nuzzo A, Favalli V et al. Translational bioinformatics: Challenges and opportunities for case-based reasoning and decision support. In Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). Vol. 6176 LNAI. 2010. p. 1-11. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)). https://doi.org/10.1007/978-3-642-14274-1_1

Bellazzi, Riccardo ; Larizza, Cristiana ; Gabetta, Matteo ; Milani, Giuseppe ; Nuzzo, Angelo ; Favalli, Valentina ; Arbustini, Eloisa. / Translational bioinformatics : Challenges and opportunities for case-based reasoning and decision support. Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). Vol. 6176 LNAI 2010. pp. 1-11 (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)).

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