TY - GEN
T1 - Translational bioinformatics
T2 - 18th International Conference on Case-Based Reasoning, ICCBR 2010
AU - Bellazzi, Riccardo
AU - Larizza, Cristiana
AU - Gabetta, Matteo
AU - Milani, Giuseppe
AU - Nuzzo, Angelo
AU - Favalli, Valentina
AU - Arbustini, Eloisa
PY - 2010
Y1 - 2010
N2 - Translational bioinformatics is bioinformatics applied to human health. Although, up to now, its main focus has been to support molecular medicine research, translational bioinformatics has now the opportunity to design clinical decision support systems based on the combination of -omics data and internet-based knowledge resources. The paper describes the state-of-art of translational bioinformatics highlighting challenges and opportunities for decision support tools and case-based reasoning. It finally reports the design of a new system for supporting diagnosis in dilated cardiomyopathy. The system is able to combine text mining, literature search and case-based retrieval.
AB - Translational bioinformatics is bioinformatics applied to human health. Although, up to now, its main focus has been to support molecular medicine research, translational bioinformatics has now the opportunity to design clinical decision support systems based on the combination of -omics data and internet-based knowledge resources. The paper describes the state-of-art of translational bioinformatics highlighting challenges and opportunities for decision support tools and case-based reasoning. It finally reports the design of a new system for supporting diagnosis in dilated cardiomyopathy. The system is able to combine text mining, literature search and case-based retrieval.
KW - decision support
KW - dilated cardiomyopathy
KW - molecular medicine
KW - Translational bioinformatics
UR - http://www.scopus.com/inward/record.url?scp=77954975347&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=77954975347&partnerID=8YFLogxK
U2 - 10.1007/978-3-642-14274-1_1
DO - 10.1007/978-3-642-14274-1_1
M3 - Conference contribution
AN - SCOPUS:77954975347
SN - 3642142737
SN - 9783642142734
VL - 6176 LNAI
T3 - Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
SP - 1
EP - 11
BT - Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Y2 - 19 July 2010 through 22 July 2010
ER -