Genetic and acquired abnormalities in complement factor H (CFH) have been associated with two different human renal diseases: haemolytic uraemic syndrome and membrano proliferative glomerulonephritis. The new genetic and pathogenetic findings in these diseases and their clinical implications for the management and cure of patients are reviewed in this paper.
- Alternative pathway of complement
- Complement factor H
- Haemolytic uraemic syndrome
- Membranoproliferative glomerulonephirtis
- Nephritic factors
ASJC Scopus subject areas