Transoral incisionless fundoplication with EsophyX® for treatment of gastro-oesphageal reflux disease

Pier Alberto Testoni, Cristian Vailati

Research output: Contribution to journalArticlepeer-review


Gastro-oesphageal reflux disease results primarily from the loss of an effective antireflux barrier, which forms a mechanical barrier against the retrograde movement of gastric content. This review describes the technique of performing a transoral incisionless fundoplication with the EsophyX® device. Transoral incisionless fundoplication reconfigures the tissue so as to establish serosa-to-serosa plications which include the muscular layers, and construct 3-5. cm long valves 200-300° in circumference. The steps of the technique, as well as complications and their management are described in detail, and a recent literature review is also provided. At present, available prospective cohort studies indicate that transoral incisionless fundoplication using the EsophyX® device may be effective in approximately half PPI-responsive gastro-oesphageal reflux disease for up to 3 years' follow-up, without troublesome procedure-related persistent side effects.

Original languageEnglish
Pages (from-to)631-635
Number of pages5
JournalDigestive and Liver Disease
Issue number8
Publication statusPublished - Aug 2012


  • Gastro-oesphageal reflux disease
  • Transoral incisionless fundoplication

ASJC Scopus subject areas

  • Gastroenterology
  • Hepatology


Dive into the research topics of 'Transoral incisionless fundoplication with EsophyX® for treatment of gastro-oesphageal reflux disease'. Together they form a unique fingerprint.

Cite this