Transurethral resection of the prostate and metastatic prostate cancer

V. Pansadoro, C. N. Sternberg, F. DePaula, A. Florio, D. Giannarelli, G. Arcangeli

Research output: Contribution to journalArticle

Abstract

Demonstration of malignant cells in blood specimens collected during transurethral resection of the prostate (TURP) has implicated TURP in the dissemination of prostatic cancer. Of 153 patients who underwent radiation therapy for prostate cancer between January 1977 and June 1990 and were retrospectively analyzed, 93 were evaluable. Fifty-nine patients required TURP before radiation therapy for prostatic obstruction (BPH and/or cancer); the remaining 34 patients underwent radiation therapy after fine-needle aspiration biopsy. No statistically significant difference in failure rate could be detected between these groups, with a failure rate of 47% (28 of 59 patients) at a median follow-up time of 49 months (range, 8 to 146 months) in the TURP group versus a failure rate of 47% (16 of 34 patients) at a median follow-up time of 50 months (range, 3 to 122 months) in the group who underwent biopsy only (Fisher's exact test, P = 0.23). Within the confines of this retrospective study, it appeared that TURP did not enhance the development of metastatic disease.

Original languageEnglish
Pages (from-to)1895-1898
Number of pages4
JournalCancer
Volume68
Issue number9
Publication statusPublished - 1991

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

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  • Cite this

    Pansadoro, V., Sternberg, C. N., DePaula, F., Florio, A., Giannarelli, D., & Arcangeli, G. (1991). Transurethral resection of the prostate and metastatic prostate cancer. Cancer, 68(9), 1895-1898.