Transuretral resection of the bladder (TURB): Analysis of complications using a modified Clavien system in an Italian real life cohort

C. De Nunzio, G. Franco, L. Cindolo, R. Autorino, A. Cicione, S. Perdonà, M. Falsaperla, M. Gacci, C. Leonardo, R. Damiano, M. De Sio, A. Tubaro

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Introduction To evaluate the applicability of a modified Clavien classification system (CCS) in grading postoperative complications of transurethral resection of bladder tumours (TURB). Materials and methods A series of patients undergoing monopolar TURB from April 2011 to March 2012 at five Italian centers were enrolled. All complications occurring within the first 30-day postoperative period were prospectively recorded and graded according to the CCS. Results Overall, 275 patients were included. Median age was 71 (63/78) years; median BMI was 28 (25.4/30.8) Kg/m2, median tumour size was 2 (1-3) cm; median number of tumour lesions was 1 (1-3). Median operative time was 30 (20/45) min. Fifty-seven complications were recorded in 43 patients. Overall postoperative morbidity rate was 16%. Most of the complications were not serious and classified as Clavien type I (42 cases; 74%) or II (8 cases, 14%). Higher grade complications were scarce: CCS IIIa in 1 case (2%) and CCS IIIb in six cases (10%). No TURB related death was reported. Six patients were re-operated due to significant bleeding or clot retention on postoperative days 2-7. On univariate (73.5 ± 38 versus 36.7 ± 21.6 min) and multivariate analysis longer operative time was an independent predictor of complications (OR: 1.06 per min, 95%CI 1.04-1.08, p = 0.001). Conclusions A modified CCS can be used as a standardized tool to objectively define the complications of TURB which confirms to be a safe procedure with a low surgical morbidity. This tool can be used to aid in patient counselling and to facilitate scientific assessment.

Original languageEnglish
Pages (from-to)90-95
Number of pages6
JournalEuropean Journal of Surgical Oncology
Issue number1
Publication statusPublished - Jan 2014


  • Bladder cancer
  • Clavien
  • Complications
  • Transurethral resection

ASJC Scopus subject areas

  • Oncology
  • Surgery

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