Treating heart failure in older and oldest old patients

Davide Liborio Vetrano, Fabrizia Lattanzio, Anna Maria Martone, Francesco Landi, Vincenzo Brandi, Eva Topinkova, Graziano Onder

Research output: Contribution to journalArticlepeer-review


Advanced age is a relevant risk factor for the heart failure (HF). The development of new pharmacol- ogical and non-pharmacological approaches has determined an improvement in survival of patients with HF, lead- ing to the selection of an older and frailer population with HF. The clinical approach to such a complex population should require clear indications to assist physicians during their daily practice, but there is a huge lack of evidence regarding the treatment of HF in the oldest among the elderly patient population. In addition, the co-occurrence of specific conditions that are extremely prevalent in older individuals with HF, such as cognitive impairment, co-morbidities, and polypharmacy, can further complicate the clinical man agement of this condition. Thus, a Davide Liborio Vetrano multidisciplinary approach with the goal of recognizing and treating conditions associated with HF may be necessary to improve the quality of care and to reduce expenditures. Several studies have assessed the effect of a comprehensive geriatric assessment and management on quality of care in HF patients, demonstrating a substantial improvement in patient outcomes and administration of the appropriate drug treatment.

Original languageEnglish
Pages (from-to)1659-1664
Number of pages6
JournalCurrent Pharmaceutical Design
Issue number13
Publication statusPublished - 2015


  • Elderly
  • Heart failure
  • Multidimensional approach
  • Oldest old
  • Polypharmacy

ASJC Scopus subject areas

  • Drug Discovery
  • Pharmacology
  • Medicine(all)


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