Treatment of asymptomatic bacterial vaginosis to prevent pre-term delivery: A randomised trial

Secondo Guaschino, Elena Ricci, Massimo Franchi, Giovanni Del Frate, Cecilia Tibaldi, Daniele De Santo, Fabio Ghezzi, Chiara Benedetto, Francesco De Seta, Fabio Parazzini

Research output: Contribution to journalArticlepeer-review

Abstract

Objectives: To evaluate the efficacy of clindamycin vaginal cream 2% once daily for 7 days in prolonging pregnancy. Study design: Randomised clinical trial of 112 women between 14 and 25 weeks of gestation with diagnosis of asymptomatic bacterial vaginosis were enrolled in a multicenter randomised trial and assigned to active or no treatment. A total of 55 women were assigned to clindamycin and 57 to no treatment. Main outcome measure: frequency of pre-term delivery. Results: The rates of pre-term delivery was 12.2% in the clindamycin group and 15.7% in the no treatment group (P=0.78). Birth weight was

Original languageEnglish
Pages (from-to)149-152
Number of pages4
JournalEuropean Journal of Obstetrics and Gynecology and Reproductive Biology
Volume110
Issue number2
DOIs
Publication statusPublished - Oct 10 2003

Keywords

  • Bacterial vaginosis
  • Clindamycin
  • Pre-term birth

ASJC Scopus subject areas

  • Obstetrics and Gynaecology
  • Reproductive Medicine

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