Treatment of asymptomatic bacterial vaginosis to prevent pre-term delivery: A randomised trial

Secondo Guaschino; Elena Ricci; Massimo Franchi; Giovanni Del Frate; Cecilia Tibaldi; Daniele De Santo; Fabio Ghezzi; Chiara Benedetto; Francesco De Seta; Fabio Parazzini

doi:10.1016/S0301-2115(03)00107-6

Treatment of asymptomatic bacterial vaginosis to prevent pre-term delivery: A randomised trial

Secondo Guaschino, Elena Ricci, Massimo Franchi, Giovanni Del Frate, Cecilia Tibaldi, Daniele De Santo, Fabio Ghezzi, Chiara Benedetto, Francesco De Seta, Fabio Parazzini

Research output: Contribution to journal › Article › peer-review

Abstract

Objectives: To evaluate the efficacy of clindamycin vaginal cream 2% once daily for 7 days in prolonging pregnancy. Study design: Randomised clinical trial of 112 women between 14 and 25 weeks of gestation with diagnosis of asymptomatic bacterial vaginosis were enrolled in a multicenter randomised trial and assigned to active or no treatment. A total of 55 women were assigned to clindamycin and 57 to no treatment. Main outcome measure: frequency of pre-term delivery. Results: The rates of pre-term delivery was 12.2% in the clindamycin group and 15.7% in the no treatment group (P=0.78). Birth weight was

Original language	English
Pages (from-to)	149-152
Number of pages	4
Journal	European Journal of Obstetrics and Gynecology and Reproductive Biology
Volume	110
Issue number	2
DOIs	https://doi.org/10.1016/S0301-2115(03)00107-6
Publication status	Published - Oct 10 2003

Keywords

Bacterial vaginosis
Clindamycin
Pre-term birth

ASJC Scopus subject areas

Obstetrics and Gynaecology
Reproductive Medicine

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10.1016/S0301-2115(03)00107-6

Cite this

Guaschino, S., Ricci, E., Franchi, M., Del Frate, G., Tibaldi, C., De Santo, D., Ghezzi, F., Benedetto, C., De Seta, F., & Parazzini, F. (2003). Treatment of asymptomatic bacterial vaginosis to prevent pre-term delivery: A randomised trial. European Journal of Obstetrics and Gynecology and Reproductive Biology, 110(2), 149-152. https://doi.org/10.1016/S0301-2115(03)00107-6

Treatment of asymptomatic bacterial vaginosis to prevent pre-term delivery : A randomised trial. / Guaschino, Secondo; Ricci, Elena; Franchi, Massimo; Del Frate, Giovanni; Tibaldi, Cecilia; De Santo, Daniele; Ghezzi, Fabio; Benedetto, Chiara; De Seta, Francesco; Parazzini, Fabio.

In: European Journal of Obstetrics and Gynecology and Reproductive Biology, Vol. 110, No. 2, 10.10.2003, p. 149-152.

Research output: Contribution to journal › Article › peer-review

Guaschino, S, Ricci, E, Franchi, M, Del Frate, G, Tibaldi, C, De Santo, D, Ghezzi, F, Benedetto, C, De Seta, F & Parazzini, F 2003, 'Treatment of asymptomatic bacterial vaginosis to prevent pre-term delivery: A randomised trial', European Journal of Obstetrics and Gynecology and Reproductive Biology, vol. 110, no. 2, pp. 149-152. https://doi.org/10.1016/S0301-2115(03)00107-6

Guaschino, Secondo ; Ricci, Elena ; Franchi, Massimo ; Del Frate, Giovanni ; Tibaldi, Cecilia ; De Santo, Daniele ; Ghezzi, Fabio ; Benedetto, Chiara ; De Seta, Francesco ; Parazzini, Fabio. / Treatment of asymptomatic bacterial vaginosis to prevent pre-term delivery : A randomised trial. In: European Journal of Obstetrics and Gynecology and Reproductive Biology. 2003 ; Vol. 110, No. 2. pp. 149-152.

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Treatment of asymptomatic bacterial vaginosis to prevent pre-term delivery: A randomised trial

Abstract

Keywords

ASJC Scopus subject areas

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