Abstract
Background: Pharmacological treatment of depression in HIV-infected patients has been found to be effective. This study assessed the efficacy and feasibility of treatment with fluoxetine and the best method of administering the drug to patients with HIV infection. Methods: Sixteen seropositive and 16 seronegative patients, equally matched for age and sex, who had Hamilton Rating Scale for Depression scores of at least 16 and who received at least 20 mg/d of fluoxetine for 8 weeks were studied. Results: Depression was alleviated in both groups. However, improvement in the seropositive patients occurred later. Interpretation: The results confirm the effectiveness of fluoxetine in treating depression in people with HIV infection. The lack of adverse effects makes this treatment particularly suitable, especially because seronegative people take longer to respond to treatment.
| Original language | English |
|---|---|
| Pages (from-to) | 293-297 |
| Number of pages | 5 |
| Journal | Journal of Psychiatry and Neuroscience |
| Volume | 23 |
| Issue number | 5 |
| Publication status | Published - 1998 |
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ASJC Scopus subject areas
- Psychiatry and Mental health
- Neuroscience(all)
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Treatment of depression in HIV-infected patients. / Cazzullo, Carlo L.; Bessone, Enrico; Bertrando, Paolo; Pedrazzoli, Laura; Cusini, Marco.
In: Journal of Psychiatry and Neuroscience, Vol. 23, No. 5, 1998, p. 293-297.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Treatment of depression in HIV-infected patients
AU - Cazzullo, Carlo L.
AU - Bessone, Enrico
AU - Bertrando, Paolo
AU - Pedrazzoli, Laura
AU - Cusini, Marco
PY - 1998
Y1 - 1998
N2 - Background: Pharmacological treatment of depression in HIV-infected patients has been found to be effective. This study assessed the efficacy and feasibility of treatment with fluoxetine and the best method of administering the drug to patients with HIV infection. Methods: Sixteen seropositive and 16 seronegative patients, equally matched for age and sex, who had Hamilton Rating Scale for Depression scores of at least 16 and who received at least 20 mg/d of fluoxetine for 8 weeks were studied. Results: Depression was alleviated in both groups. However, improvement in the seropositive patients occurred later. Interpretation: The results confirm the effectiveness of fluoxetine in treating depression in people with HIV infection. The lack of adverse effects makes this treatment particularly suitable, especially because seronegative people take longer to respond to treatment.
AB - Background: Pharmacological treatment of depression in HIV-infected patients has been found to be effective. This study assessed the efficacy and feasibility of treatment with fluoxetine and the best method of administering the drug to patients with HIV infection. Methods: Sixteen seropositive and 16 seronegative patients, equally matched for age and sex, who had Hamilton Rating Scale for Depression scores of at least 16 and who received at least 20 mg/d of fluoxetine for 8 weeks were studied. Results: Depression was alleviated in both groups. However, improvement in the seropositive patients occurred later. Interpretation: The results confirm the effectiveness of fluoxetine in treating depression in people with HIV infection. The lack of adverse effects makes this treatment particularly suitable, especially because seronegative people take longer to respond to treatment.
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M3 - Article
C2 - 9846034
AN - SCOPUS:0032438358
VL - 23
SP - 293
EP - 297
JO - Journal of Psychiatry and Neuroscience
JF - Journal of Psychiatry and Neuroscience
SN - 1180-4882
IS - 5
ER -