Treatment of endolymphatic sac tumour (Papillary adenocarcinoma) of the temporal bone

Arturo Mario Poletti, Siba Prasad Dubey, Giovanni Colombo, Giovanni Cugini, Antonio Mazzoni

Research output: Contribution to journalArticlepeer-review

Abstract

Aim: To define a better treatment of sporadic endolymphatic sac tumours (ELST) analysing our experience and literature available data. Background: ELST can arise as sporadic case (rare) or as a part of von Hippel-Lindau (VHL) disease. It is a low grade malignancy with local spread by continuity. Materials and methods: we described our experience with 7 cases with up to date follow up. Results: Five cases were free of disease after first surgical procedure. One case had recurrence in the temporal lobe after 12 years. One case had two surgical procedures followed by irradiation and died five years after radiotherapy with a slow disease progression. Conclusion: With increasing expertise in the skull base surgery, complete tumour excisions are achieved in majority of the more recent cases and appear to be the treatment of choice. External irradiation is also used as palliative measures with doubtful effectiveness. Some recent reports showed encouraging results with gamma knife radiosurgery.

Original languageEnglish
JournalReports of Practical Oncology and Radiotherapy
DOIs
Publication statusAccepted/In press - Oct 7 2014

Keywords

  • Endolymphatic sac
  • Papillary adenocarcinoma
  • Surgery
  • Temporal bone
  • Tumour

ASJC Scopus subject areas

  • Cancer Research
  • Oncology
  • Radiology Nuclear Medicine and imaging

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