Treatment of FIGO stage Ib cervical carcinoma with nodal involvement

F. Pedulla, M. G. Centurioni, G. Foglia, I. Ferrari, M. Orsatti, V. Vitale, N. Ragni

Research output: Contribution to journalArticle

Abstract

One hundred and eighty one patients with stage Ib cervical cancer underwent hysterectomy with pelvic lymphadenectomy. The overall incidence of lymph node metastases was 20%. Twenty seven (71%) patients with nodal involvement were treated by external radiotherapy (TCT) and 11 (29%) by both chemotherapy and radiotherapy (Lin. Acc.). The overall survival at 5 years was 80%; it was 43% for patients with positive nodes and 89% for patients without metastatic nodal disease. The 3 year survival of patients with positive nodes who underwent radiation therapy by TCT was 58%, while it was 72% for those treated by chemotherapy plus radiotherapy. We observed a recurrence in 23% of the cases, 52% in patients with positive nodes and 15% in those with negative nodes. The association chemo-radiotherapy in patients with metastatic lymph nodes seems to improve the survival and reduce the recurrence rate.

Original languageEnglish
Pages (from-to)59-64
Number of pages6
JournalEuropean Journal of Gynaecological Oncology
Volume15
Issue number1
Publication statusPublished - 1994

ASJC Scopus subject areas

  • Obstetrics and Gynaecology
  • Oncology

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    Pedulla, F., Centurioni, M. G., Foglia, G., Ferrari, I., Orsatti, M., Vitale, V., & Ragni, N. (1994). Treatment of FIGO stage Ib cervical carcinoma with nodal involvement. European Journal of Gynaecological Oncology, 15(1), 59-64.