Treatment of giant Bowen's disease with sequential use of photodynamic therapy and imiquimod cream

Eleni Sotiriou; Aimilios Lallas; Zoi Apalla; Demetris Ioannides

doi:10.1111/j.1600-0781.2011.00586.x

Treatment of giant Bowen's disease with sequential use of photodynamic therapy and imiquimod cream

Eleni Sotiriou, Aimilios Lallas, Zoi Apalla, Demetris Ioannides

Arcispedale Santa Maria Nuova

Research output: Contribution to journal › Article › peer-review

Abstract

We present a 79-year-old man with a 2-year history of Bowen's disease. The 10 × 10 plaque was located on the right frontotemporal area. The patient was treated with two photodynamic therapy (PDT) sessions, performed 1 week apart, followed by five times per week application of imiquimod 5% cream for 6 consecutive weeks. Complete clinical and histological response was achieved 3 months after treatment was completed. The patient remains recurrence free 12 months after treatment. Cosmetic outcome was evaluated as fair because of residual erythema. Long-term follow-up is mandatory for assessment of recurrences. Further studies are needed in order to confirm the improved outcome using the combination of PDT and imiquimod cream.

Original language	English
Pages (from-to)	164-166
Number of pages	3
Journal	Photodermatology Photoimmunology and Photomedicine
Volume	27
Issue number	3
DOIs	https://doi.org/10.1111/j.1600-0781.2011.00586.x
Publication status	Published - Jun 2011

Keywords

Bowen's disease
Imiquimod cream
Photodynamic therapy
Treatment

ASJC Scopus subject areas

Dermatology
Immunology and Allergy
Immunology
Radiology Nuclear Medicine and imaging

Access to Document

10.1111/j.1600-0781.2011.00586.x

Fingerprint Dive into the research topics of 'Treatment of giant Bowen's disease with sequential use of photodynamic therapy and imiquimod cream'. Together they form a unique fingerprint.

Cite this

@article{3d00401821c7496892dca78eb32a779b,

title = "Treatment of giant Bowen's disease with sequential use of photodynamic therapy and imiquimod cream",

abstract = "We present a 79-year-old man with a 2-year history of Bowen's disease. The 10 × 10 plaque was located on the right frontotemporal area. The patient was treated with two photodynamic therapy (PDT) sessions, performed 1 week apart, followed by five times per week application of imiquimod 5% cream for 6 consecutive weeks. Complete clinical and histological response was achieved 3 months after treatment was completed. The patient remains recurrence free 12 months after treatment. Cosmetic outcome was evaluated as fair because of residual erythema. Long-term follow-up is mandatory for assessment of recurrences. Further studies are needed in order to confirm the improved outcome using the combination of PDT and imiquimod cream.",

keywords = "Bowen's disease, Imiquimod cream, Photodynamic therapy, Treatment",

author = "Eleni Sotiriou and Aimilios Lallas and Zoi Apalla and Demetris Ioannides",

year = "2011",

month = jun,

doi = "10.1111/j.1600-0781.2011.00586.x",

language = "English",

volume = "27",

pages = "164--166",

journal = "Photo-dermatology",

issn = "0905-4383",

publisher = "Blackwell Munksgaard",

number = "3",

}

TY - JOUR

T1 - Treatment of giant Bowen's disease with sequential use of photodynamic therapy and imiquimod cream

AU - Sotiriou, Eleni

AU - Lallas, Aimilios

AU - Apalla, Zoi

AU - Ioannides, Demetris

PY - 2011/6

Y1 - 2011/6

N2 - We present a 79-year-old man with a 2-year history of Bowen's disease. The 10 × 10 plaque was located on the right frontotemporal area. The patient was treated with two photodynamic therapy (PDT) sessions, performed 1 week apart, followed by five times per week application of imiquimod 5% cream for 6 consecutive weeks. Complete clinical and histological response was achieved 3 months after treatment was completed. The patient remains recurrence free 12 months after treatment. Cosmetic outcome was evaluated as fair because of residual erythema. Long-term follow-up is mandatory for assessment of recurrences. Further studies are needed in order to confirm the improved outcome using the combination of PDT and imiquimod cream.

AB - We present a 79-year-old man with a 2-year history of Bowen's disease. The 10 × 10 plaque was located on the right frontotemporal area. The patient was treated with two photodynamic therapy (PDT) sessions, performed 1 week apart, followed by five times per week application of imiquimod 5% cream for 6 consecutive weeks. Complete clinical and histological response was achieved 3 months after treatment was completed. The patient remains recurrence free 12 months after treatment. Cosmetic outcome was evaluated as fair because of residual erythema. Long-term follow-up is mandatory for assessment of recurrences. Further studies are needed in order to confirm the improved outcome using the combination of PDT and imiquimod cream.

KW - Bowen's disease

KW - Imiquimod cream

KW - Photodynamic therapy

KW - Treatment

UR - http://www.scopus.com/inward/record.url?scp=79955621524&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=79955621524&partnerID=8YFLogxK

U2 - 10.1111/j.1600-0781.2011.00586.x

DO - 10.1111/j.1600-0781.2011.00586.x

M3 - Article

C2 - 21535173

AN - SCOPUS:79955621524

VL - 27

SP - 164

EP - 166

JO - Photo-dermatology

JF - Photo-dermatology

SN - 0905-4383

IS - 3

ER -