Treatment of heart failure with autologous skeletal myoblasts

Juan C. Chachques, Barbara Cattadori, Jesus Herreros, Felipe Prosper, Jorge C. Trainini, Didier Blanchard, Jean Noël Fabiani, Alain Carpentier

Research output: Contribution to journalArticle

Abstract

Background: The management of patients with heart failure is a daily challenge for cardiologists and cardiac surgeons. Pharmacotherapy, atrio-biventricular resynchronization, myocardial revascularization, valve repair techniques, latissimus dorsi cardiomyoplasty, acorn cardiac support device, heart transplantation and mechanical assist devices do not cover all the needs. The recent progress in cellular and molecular biology allows the development of new therapies for heart failure. Transplantation of Autologous Cells: One of the most innovative consists in the transplantation of autologous ex-vivo expanded cells into the myocardium for heart muscle regeneration. This approach is called "cellular cardiomyoplasty".

Original languageEnglish
Pages (from-to)570-578
Number of pages9
JournalHerz
Volume27
Issue number7
DOIs
Publication statusPublished - Nov 2002

Keywords

  • Cell transplantation
  • Cellular biology
  • Cellular cardiomyoplasty
  • Congestive heart failure
  • Myoblasts
  • Myocardial infarction

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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    Chachques, J. C., Cattadori, B., Herreros, J., Prosper, F., Trainini, J. C., Blanchard, D., Fabiani, J. N., & Carpentier, A. (2002). Treatment of heart failure with autologous skeletal myoblasts. Herz, 27(7), 570-578. https://doi.org/10.1007/s00059-002-2422-3