Treatment of hyperprolactinaemia with metergoliie for periods up to 5 years: Clinical and biological tolerability

L. Falsetti, A. M. Voltolini, M. Schimberni, A. E. Pontiroli

Research output: Contribution to journalArticle

Abstract

Forty patients with hyperprolactinaemia were treated with metergoline (8 to 12 mg/day) for periods up to 5 years. Analysis of the results of clinical and biological tolerability showed that treatment was generally well tolerated and although 28 patients complained of drug-related side-effects of various kinds, principally nausea, these were usually mild, present at the beginning of treatment and disappeared spontaneously in spite of continued metergoline administration over a prolonged period. No patient stopped treatment because of side-effects. Laboratory parameters also stayed within normal levels and there was no evidence of any alterations in the ECG. It is concluded, therefore, that metergoline is a well-tolerated as well as an effective ergolinic compound for use in those patients in whom prolonged treatment with a prolactin-lowering drug is considered necessaiy.

Original languageEnglish
Pages (from-to)327-332
Number of pages6
JournalCurrent Medical Research and Opinion
Volume8
Issue number5
DOIs
Publication statusPublished - 1983

Keywords

  • Hyperprolactinaemia
  • Metergoline

ASJC Scopus subject areas

  • Medicine(all)

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