Treatment of intracranial meningiomas in patients over 70 years old

C. Arienta, M. Caroli, F. Crotti, R. Villani

Research output: Contribution to journalArticle

55 Citations (Scopus)

Abstract

The neurosurgeon often finds himself in the position to having to decide whether or not to operate on an elderly patient suffering from intracranial meningioma. The decision is rarely easy and the results often disappointing. We studied 46 cases of intracranial meningioma in patients over 70 years of age, 34 patients were operated on while 12 patients were not, although both groups were subjected to long term follow-up. The operative mortality rate was 12%, a rate which increased to 20% at 3 months follow-up. Various unfavourable prognostic factors were taken into consideration, the most significant of which were: poor overall clinical condition, peritumoural oedema, the presence of diabetes mellitus and the duration of surgery. A scored grading system was created to standardize surgical indications in elderly patients with cerebral meningioma. An analysis of the grading system, when applied to patients submitted to surgery, showed that the deceased patients within 3 months of surgery had a score which varied from 7 to 12, with a mean score of 10. The surviving patients had a score averaging from 10 to 16 with a mean of 13. The patients with the lowest scores (7-9) had a 100% mortality rate while those in the upper ranges (13-16) demonstrated a mortality rate of 0%. Among the conservatively treated patients the worst outcome was seen in patients with a grading equal to or less than 12.

Original languageEnglish
Pages (from-to)47-55
Number of pages9
JournalActa Neurochirurgica
Volume107
Issue number1-2
DOIs
Publication statusPublished - Mar 1990

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Meningioma
Therapeutics
Mortality
Edema
Diabetes Mellitus

Keywords

  • clinical-radiological grading
  • elderly patients
  • Intracranial meningioma

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

Cite this

Treatment of intracranial meningiomas in patients over 70 years old. / Arienta, C.; Caroli, M.; Crotti, F.; Villani, R.

In: Acta Neurochirurgica, Vol. 107, No. 1-2, 03.1990, p. 47-55.

Research output: Contribution to journalArticle

Arienta, C. ; Caroli, M. ; Crotti, F. ; Villani, R. / Treatment of intracranial meningiomas in patients over 70 years old. In: Acta Neurochirurgica. 1990 ; Vol. 107, No. 1-2. pp. 47-55.
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