Treatment of lymphoma in the elderly

An update

U. Tirelli, V. Zagonel, D. Errante, L. Fratino, S. Monfardini

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Recent studies specifically directed toward assessing the outcome of older patients with non-Hodgkin's lymphoma (NHL) indicate that age per se is an important and independent prognostic factor for response and survival. Prospective studies have addressed therapeutic approaches in these patients. Direct comparison of trial results is difficult since different age limits were set for the inclusion of patients in study. These studies suggest that older patients with aggressive NHL should be treated with curative intent. We report on selected prospective clinical trials of the literature and the Aviano Group experience in the treatment of NHL in the elderly. In particular we refer our data of a randomized study (CHOP vs VMP), conducted within the EORTC Lymphoma Group, and the results obtained with chemotherapy and granulocyte colony-stimulating factor.

Original languageEnglish
Pages (from-to)24-29
Number of pages6
JournalRays - International Journal of Radiological Sciences
Volume22
Issue number1 SUPPL.
Publication statusPublished - 1997

Fingerprint

Lymphoma
Non-Hodgkin's Lymphoma
Granulocyte Colony-Stimulating Factor
Therapeutics
Clinical Trials
Prospective Studies
Drug Therapy
Survival

Keywords

  • Elderly
  • Non-Hodgkin's lymphoma
  • Treatment

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Treatment of lymphoma in the elderly : An update. / Tirelli, U.; Zagonel, V.; Errante, D.; Fratino, L.; Monfardini, S.

In: Rays - International Journal of Radiological Sciences, Vol. 22, No. 1 SUPPL., 1997, p. 24-29.

Research output: Contribution to journalArticle

Tirelli, U, Zagonel, V, Errante, D, Fratino, L & Monfardini, S 1997, 'Treatment of lymphoma in the elderly: An update', Rays - International Journal of Radiological Sciences, vol. 22, no. 1 SUPPL., pp. 24-29.
Tirelli, U. ; Zagonel, V. ; Errante, D. ; Fratino, L. ; Monfardini, S. / Treatment of lymphoma in the elderly : An update. In: Rays - International Journal of Radiological Sciences. 1997 ; Vol. 22, No. 1 SUPPL. pp. 24-29.
@article{f965eb6d3f4448458dea030d45bf6d5b,
title = "Treatment of lymphoma in the elderly: An update",
abstract = "Recent studies specifically directed toward assessing the outcome of older patients with non-Hodgkin's lymphoma (NHL) indicate that age per se is an important and independent prognostic factor for response and survival. Prospective studies have addressed therapeutic approaches in these patients. Direct comparison of trial results is difficult since different age limits were set for the inclusion of patients in study. These studies suggest that older patients with aggressive NHL should be treated with curative intent. We report on selected prospective clinical trials of the literature and the Aviano Group experience in the treatment of NHL in the elderly. In particular we refer our data of a randomized study (CHOP vs VMP), conducted within the EORTC Lymphoma Group, and the results obtained with chemotherapy and granulocyte colony-stimulating factor.",
keywords = "Elderly, Non-Hodgkin's lymphoma, Treatment",
author = "U. Tirelli and V. Zagonel and D. Errante and L. Fratino and S. Monfardini",
year = "1997",
language = "English",
volume = "22",
pages = "24--29",
journal = "Rays - International Journal of Radiological Sciences",
issn = "0390-7740",
publisher = "Centro Minerva Medica",
number = "1 SUPPL.",

}

TY - JOUR

T1 - Treatment of lymphoma in the elderly

T2 - An update

AU - Tirelli, U.

AU - Zagonel, V.

AU - Errante, D.

AU - Fratino, L.

AU - Monfardini, S.

PY - 1997

Y1 - 1997

N2 - Recent studies specifically directed toward assessing the outcome of older patients with non-Hodgkin's lymphoma (NHL) indicate that age per se is an important and independent prognostic factor for response and survival. Prospective studies have addressed therapeutic approaches in these patients. Direct comparison of trial results is difficult since different age limits were set for the inclusion of patients in study. These studies suggest that older patients with aggressive NHL should be treated with curative intent. We report on selected prospective clinical trials of the literature and the Aviano Group experience in the treatment of NHL in the elderly. In particular we refer our data of a randomized study (CHOP vs VMP), conducted within the EORTC Lymphoma Group, and the results obtained with chemotherapy and granulocyte colony-stimulating factor.

AB - Recent studies specifically directed toward assessing the outcome of older patients with non-Hodgkin's lymphoma (NHL) indicate that age per se is an important and independent prognostic factor for response and survival. Prospective studies have addressed therapeutic approaches in these patients. Direct comparison of trial results is difficult since different age limits were set for the inclusion of patients in study. These studies suggest that older patients with aggressive NHL should be treated with curative intent. We report on selected prospective clinical trials of the literature and the Aviano Group experience in the treatment of NHL in the elderly. In particular we refer our data of a randomized study (CHOP vs VMP), conducted within the EORTC Lymphoma Group, and the results obtained with chemotherapy and granulocyte colony-stimulating factor.

KW - Elderly

KW - Non-Hodgkin's lymphoma

KW - Treatment

UR - http://www.scopus.com/inward/record.url?scp=0030762526&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0030762526&partnerID=8YFLogxK

M3 - Article

VL - 22

SP - 24

EP - 29

JO - Rays - International Journal of Radiological Sciences

JF - Rays - International Journal of Radiological Sciences

SN - 0390-7740

IS - 1 SUPPL.

ER -