Abstract
| Original language | English |
|---|---|
| Pages (from-to) | 3-14 |
| Number of pages | 12 |
| Journal | Tumori |
| Volume | 105 |
| Issue number | 5_suppl |
| DOIs | |
| Publication status | Published - 2019 |
Keywords
- AIOM
- guidelines
- non-small cell lung cancer
- recommendations
- anaplastic lymphoma kinase
- antineoplastic agent
- epidermal growth factor receptor
- Article
- cancer staging
- cancer therapy
- health care personnel
- human
- maintenance therapy
- non small cell lung cancer
- oncogene
- oncologist
- physician
- practice guideline
- systemic therapy
- Italy
- lung tumor
- meta analysis
- oncology
- standards
- Antineoplastic Agents
- Carcinoma, Non-Small-Cell Lung
- Health Personnel
- Humans
- Lung Neoplasms
- Medical Oncology
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Treatment of metastatic non-small cell lung cancer: 2018 guidelines of the Italian Association of Medical Oncology (AIOM). / Facchinetti, F.; Pilotto, S.; Metro, G. et al.
In: Tumori, Vol. 105, No. 5_suppl, 2019, p. 3-14.Research output: Contribution to journal › Article › peer-review
}
TY - JOUR
T1 - Treatment of metastatic non-small cell lung cancer: 2018 guidelines of the Italian Association of Medical Oncology (AIOM)
AU - Facchinetti, F.
AU - Pilotto, S.
AU - Metro, G.
AU - Baldini, E.
AU - Bertolaccini, L.
AU - Cappuzzo, F.
AU - Delmonte, A.
AU - Gasparini, S.
AU - Inno, A.
AU - Marchetti, A.
AU - Passiglia, F.
AU - Puma, F.
AU - Ricardi, U.
AU - Rossi, A.
AU - Crinò, L.
AU - Novello, S.
N1 - Cited By :1 Export Date: 26 February 2020 CODEN: TUMOA Correspondence Address: Novello, S.; Department of Oncology, University of Turin, San Luigi HospitalItaly; email: silvia.novello@unito.it Chemicals/CAS: anaplastic lymphoma kinase, 166433-56-3; epidermal growth factor receptor, 79079-06-4; Antineoplastic Agents Funding details: Università degli Studi di Verona Funding text 1: 1INSERM U981, Gustave Roussy Cancer Campus, Université Paris Saclay, Villejuif, France 2Medical Oncology, University of Verona, Verona University Hospital, Verona, Italy 3Medical Oncology, Santa Maria della Misericordia Hospital, Azienda Ospedaliera di Perugia, Perugia, Italy 4Department of Oncology, S. Luca Hospital, Lucca, Italy 5Division of Thoracic Surgery, IEO, European Institute of Oncology IRCCS, Milan, Italy 6Department of Oncology and Hematology, AUSL Romagna, Ravenna, Italy 7Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Meldola, Italy 8Department of Biologic Sciences and Public Health, Polytechnic University of Marche Region; Pulmonary Diseases Unit, Azienda Ospedali Riuniti, Ancona, Italy 9Medical Oncology, IRCCS Ospedale Sacro Cuore Don Calabria, Negrar, Verona, Italy References: Bray, F., Ferlay, J., Soerjomataram, I., Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries (2018) CA Cancer J Clin, 68, pp. 394-424; (2018) I Numeri Del Cancro in Italia 2018, , Milan, AIOM; Jemal, A., Miller, K.D., Ma, J., Higher lung cancer incidence in young women than young men in the United States (2018) N Engl J Med, 378, pp. 1999-2009; Trama, A., Boffi, R., Contiero, P., Trends in lung cancer and smoking behavior in Italy: an alarm bell for women (2017) Tumori, 103, pp. 543-550; 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PY - 2019
Y1 - 2019
N2 - The treatment landscape of metastatic non-small cell lung cancer (NSCLC) has dramatically evolved in recent years, since the recognition of several clinical–biological entities requiring personalized treatment approaches, leading to significant improvements in patients’ survival outcomes. In particular, targeted therapies acting against EGFR, ALK, and ROS1, and immunotherapeutic agents modulating the PD-1/PD-L1 axis, represent new milestones in the treatment of advanced disease, supporting a chemotherapy backbone within a multidisciplinary model. The Italian Association of Medical Oncology (AIOM) has developed evidence-based guidelines for the management of lung tumors. Given the epidemiologic relevance, this report is dedicated to the treatment of advanced/metastatic NSCLC. These guidelines serve as a practical tool for oncologists, physicians, and other healthcare professionals to easily embrace the updated key points of NSCLC treatment strategies. Considering the upcoming introduction of potential new standards of care in several disease settings, these guidelines represent a benchmark from which to move forward. © The Author(s) 2019.
AB - The treatment landscape of metastatic non-small cell lung cancer (NSCLC) has dramatically evolved in recent years, since the recognition of several clinical–biological entities requiring personalized treatment approaches, leading to significant improvements in patients’ survival outcomes. In particular, targeted therapies acting against EGFR, ALK, and ROS1, and immunotherapeutic agents modulating the PD-1/PD-L1 axis, represent new milestones in the treatment of advanced disease, supporting a chemotherapy backbone within a multidisciplinary model. The Italian Association of Medical Oncology (AIOM) has developed evidence-based guidelines for the management of lung tumors. Given the epidemiologic relevance, this report is dedicated to the treatment of advanced/metastatic NSCLC. These guidelines serve as a practical tool for oncologists, physicians, and other healthcare professionals to easily embrace the updated key points of NSCLC treatment strategies. Considering the upcoming introduction of potential new standards of care in several disease settings, these guidelines represent a benchmark from which to move forward. © The Author(s) 2019.
KW - AIOM
KW - guidelines
KW - non-small cell lung cancer
KW - recommendations
KW - anaplastic lymphoma kinase
KW - antineoplastic agent
KW - epidermal growth factor receptor
KW - Article
KW - cancer staging
KW - cancer therapy
KW - health care personnel
KW - human
KW - maintenance therapy
KW - non small cell lung cancer
KW - oncogene
KW - oncologist
KW - physician
KW - practice guideline
KW - systemic therapy
KW - Italy
KW - lung tumor
KW - meta analysis
KW - oncology
KW - standards
KW - Antineoplastic Agents
KW - Carcinoma, Non-Small-Cell Lung
KW - Health Personnel
KW - Humans
KW - Lung Neoplasms
KW - Medical Oncology
U2 - 10.1177/0300891619857418
DO - 10.1177/0300891619857418
M3 - Article
VL - 105
SP - 3
EP - 14
JO - Tumori
JF - Tumori
SN - 0300-8916
IS - 5_suppl
ER -