Trattamento del neuroblastoma: ruolo dell'irradiazione corporea totale.

Translated title of the contribution: Treatment of neuroblastoma: role of total body irradiation

P. Franzone, R. Corvò, G. Dini, G. P. Perin, D. Scarpati

Research output: Contribution to journalArticlepeer-review


Advanced neuroblastoma, scarcely responsive to conventional therapies, can take advantage of high dose chemio-radiotherapic treatment followed by bone marrow transplant. Nineteen young patients underwent an ablative chemotherapy with high dose Vincristine and Melphalan plus Total Body Irradiation in Genoa, Italy; all of them underwent autologous bone marrow transplantation. Fourteen children were in complete remission (CR), 5 had residual disease. Thirteen are alive after a median of 7 months following transplant; 9 are in CR; 4 have disease; 1 died for toxicity; 5 for relapse. The results seem to suggest that ablative therapy should be given to patients in CR. Toxicity was not remarkable mainly as far as TBI is concerned.

Translated title of the contributionTreatment of neuroblastoma: role of total body irradiation
Original languageItalian
Pages (from-to)959-962
Number of pages4
JournalRadiologia Medica
Issue number12
Publication statusPublished - Dec 1986

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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