Treatment of neurogenic bowel dysfunction using transanal irrigation: A multicenter Italian study

G. Del Popolo, G. Mosiello, C. Pilati, M. Lamartina, F. Battaglino, P. Buffa, T. Redaelli, G. Lamberti, M. Menarini, P. Di Benedetto, M. De Gennaro

Research output: Contribution to journalArticlepeer-review


Study design: Thirty-six patients with unsatisfactory treatment of neurogenic bowel dysfunctions (NBD) were enrolled from Spinal Units and Rehabilitation Centers in Italy. Treatment was for 3 weeks using a newly developed integrated system with an enema continence catheter for transanal irrigation (Peristeen, Coloplast A/S Kokkedal Denmark). Objectives: To evaluate the effects of Peristeen Anal Irrigation on NBD and patient quality of life (QoL). Setting: Italy. Methods: Lesion level, ambulatory status and hand functionality were determined in all patients. NBD symptoms and QoL were evaluated before and after treatment, using a specific questionnaire. Statistical analysis was performed using McNemar Test and Sign Test. Results: Thirty-six patients were enrolled, and 32 patients completed the study. At the end of the treatment, 28.6% of patients reduced or eliminated their use of pharmaceuticals. Twenty-four patients became less dependent on their caregiver. There was a significant increase in patients' opinion of their intestinal functionality (P=0.001), QoL score (P=0.001) and their answers regarding their degree of satisfaction (P=0.001). A successful outcome was recorded for 68% of patients with fecal incontinence, and for 63% of patients with constipation. Conclusion: Peristeen Anal Irrigation is a simple therapeutic method for managing NBD and improving QoL. It should be considered as the treatment of choice for NBD, playing a role in the neurogenic bowel analogous to that of intermittent clean catheterization in bladder treatment.

Original languageEnglish
Pages (from-to)517-522
Number of pages6
JournalSpinal Cord
Issue number7
Publication statusPublished - Jul 2008


  • Constipation
  • Fecal incontinence
  • Neurological diseases
  • Quality of life

ASJC Scopus subject areas

  • Clinical Neurology


Dive into the research topics of 'Treatment of neurogenic bowel dysfunction using transanal irrigation: A multicenter Italian study'. Together they form a unique fingerprint.

Cite this