Treatment of neurogenic bowel dysfunction using transanal irrigation: A multicenter Italian study

G. Del Popolo, G. Mosiello, C. Pilati, M. Lamartina, F. Battaglino, P. Buffa, T. Redaelli, G. Lamberti, M. Menarini, P. Di Benedetto, M. De Gennaro

Research output: Contribution to journalArticle

53 Citations (Scopus)

Abstract

Study design: Thirty-six patients with unsatisfactory treatment of neurogenic bowel dysfunctions (NBD) were enrolled from Spinal Units and Rehabilitation Centers in Italy. Treatment was for 3 weeks using a newly developed integrated system with an enema continence catheter for transanal irrigation (Peristeen, Coloplast A/S Kokkedal Denmark). Objectives: To evaluate the effects of Peristeen Anal Irrigation on NBD and patient quality of life (QoL). Setting: Italy. Methods: Lesion level, ambulatory status and hand functionality were determined in all patients. NBD symptoms and QoL were evaluated before and after treatment, using a specific questionnaire. Statistical analysis was performed using McNemar Test and Sign Test. Results: Thirty-six patients were enrolled, and 32 patients completed the study. At the end of the treatment, 28.6% of patients reduced or eliminated their use of pharmaceuticals. Twenty-four patients became less dependent on their caregiver. There was a significant increase in patients' opinion of their intestinal functionality (P=0.001), QoL score (P=0.001) and their answers regarding their degree of satisfaction (P=0.001). A successful outcome was recorded for 68% of patients with fecal incontinence, and for 63% of patients with constipation. Conclusion: Peristeen Anal Irrigation is a simple therapeutic method for managing NBD and improving QoL. It should be considered as the treatment of choice for NBD, playing a role in the neurogenic bowel analogous to that of intermittent clean catheterization in bladder treatment.

Original languageEnglish
Pages (from-to)517-522
Number of pages6
JournalSpinal Cord
Volume46
Issue number7
DOIs
Publication statusPublished - Jul 2008

Fingerprint

Neurogenic Bowel
Multicenter Studies
Quality of Life
Therapeutics
Italy
Intermittent Urethral Catheterization
Fecal Incontinence
Rehabilitation Centers
Enema
Denmark
Constipation
Caregivers

Keywords

  • Constipation
  • Fecal incontinence
  • Neurological diseases
  • Quality of life

ASJC Scopus subject areas

  • Clinical Neurology

Cite this

Treatment of neurogenic bowel dysfunction using transanal irrigation : A multicenter Italian study. / Del Popolo, G.; Mosiello, G.; Pilati, C.; Lamartina, M.; Battaglino, F.; Buffa, P.; Redaelli, T.; Lamberti, G.; Menarini, M.; Di Benedetto, P.; De Gennaro, M.

In: Spinal Cord, Vol. 46, No. 7, 07.2008, p. 517-522.

Research output: Contribution to journalArticle

Del Popolo, G, Mosiello, G, Pilati, C, Lamartina, M, Battaglino, F, Buffa, P, Redaelli, T, Lamberti, G, Menarini, M, Di Benedetto, P & De Gennaro, M 2008, 'Treatment of neurogenic bowel dysfunction using transanal irrigation: A multicenter Italian study', Spinal Cord, vol. 46, no. 7, pp. 517-522. https://doi.org/10.1038/sj.sc.3102167
Del Popolo, G. ; Mosiello, G. ; Pilati, C. ; Lamartina, M. ; Battaglino, F. ; Buffa, P. ; Redaelli, T. ; Lamberti, G. ; Menarini, M. ; Di Benedetto, P. ; De Gennaro, M. / Treatment of neurogenic bowel dysfunction using transanal irrigation : A multicenter Italian study. In: Spinal Cord. 2008 ; Vol. 46, No. 7. pp. 517-522.
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