Abstract
Study design: Thirty-six patients with unsatisfactory treatment of neurogenic bowel dysfunctions (NBD) were enrolled from Spinal Units and Rehabilitation Centers in Italy. Treatment was for 3 weeks using a newly developed integrated system with an enema continence catheter for transanal irrigation (Peristeen, Coloplast A/S Kokkedal Denmark). Objectives: To evaluate the effects of Peristeen Anal Irrigation on NBD and patient quality of life (QoL). Setting: Italy. Methods: Lesion level, ambulatory status and hand functionality were determined in all patients. NBD symptoms and QoL were evaluated before and after treatment, using a specific questionnaire. Statistical analysis was performed using McNemar Test and Sign Test. Results: Thirty-six patients were enrolled, and 32 patients completed the study. At the end of the treatment, 28.6% of patients reduced or eliminated their use of pharmaceuticals. Twenty-four patients became less dependent on their caregiver. There was a significant increase in patients' opinion of their intestinal functionality (P=0.001), QoL score (P=0.001) and their answers regarding their degree of satisfaction (P=0.001). A successful outcome was recorded for 68% of patients with fecal incontinence, and for 63% of patients with constipation. Conclusion: Peristeen Anal Irrigation is a simple therapeutic method for managing NBD and improving QoL. It should be considered as the treatment of choice for NBD, playing a role in the neurogenic bowel analogous to that of intermittent clean catheterization in bladder treatment.
| Original language | English |
|---|---|
| Pages (from-to) | 517-522 |
| Number of pages | 6 |
| Journal | Spinal Cord |
| Volume | 46 |
| Issue number | 7 |
| DOIs | |
| Publication status | Published - Jul 2008 |
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Keywords
- Constipation
- Fecal incontinence
- Neurological diseases
- Quality of life
ASJC Scopus subject areas
- Clinical Neurology
Cite this
Treatment of neurogenic bowel dysfunction using transanal irrigation : A multicenter Italian study. / Del Popolo, G.; Mosiello, G.; Pilati, C.; Lamartina, M.; Battaglino, F.; Buffa, P.; Redaelli, T.; Lamberti, G.; Menarini, M.; Di Benedetto, P.; De Gennaro, M.
In: Spinal Cord, Vol. 46, No. 7, 07.2008, p. 517-522.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Treatment of neurogenic bowel dysfunction using transanal irrigation
T2 - A multicenter Italian study
AU - Del Popolo, G.
AU - Mosiello, G.
AU - Pilati, C.
AU - Lamartina, M.
AU - Battaglino, F.
AU - Buffa, P.
AU - Redaelli, T.
AU - Lamberti, G.
AU - Menarini, M.
AU - Di Benedetto, P.
AU - De Gennaro, M.
PY - 2008/7
Y1 - 2008/7
N2 - Study design: Thirty-six patients with unsatisfactory treatment of neurogenic bowel dysfunctions (NBD) were enrolled from Spinal Units and Rehabilitation Centers in Italy. Treatment was for 3 weeks using a newly developed integrated system with an enema continence catheter for transanal irrigation (Peristeen, Coloplast A/S Kokkedal Denmark). Objectives: To evaluate the effects of Peristeen Anal Irrigation on NBD and patient quality of life (QoL). Setting: Italy. Methods: Lesion level, ambulatory status and hand functionality were determined in all patients. NBD symptoms and QoL were evaluated before and after treatment, using a specific questionnaire. Statistical analysis was performed using McNemar Test and Sign Test. Results: Thirty-six patients were enrolled, and 32 patients completed the study. At the end of the treatment, 28.6% of patients reduced or eliminated their use of pharmaceuticals. Twenty-four patients became less dependent on their caregiver. There was a significant increase in patients' opinion of their intestinal functionality (P=0.001), QoL score (P=0.001) and their answers regarding their degree of satisfaction (P=0.001). A successful outcome was recorded for 68% of patients with fecal incontinence, and for 63% of patients with constipation. Conclusion: Peristeen Anal Irrigation is a simple therapeutic method for managing NBD and improving QoL. It should be considered as the treatment of choice for NBD, playing a role in the neurogenic bowel analogous to that of intermittent clean catheterization in bladder treatment.
AB - Study design: Thirty-six patients with unsatisfactory treatment of neurogenic bowel dysfunctions (NBD) were enrolled from Spinal Units and Rehabilitation Centers in Italy. Treatment was for 3 weeks using a newly developed integrated system with an enema continence catheter for transanal irrigation (Peristeen, Coloplast A/S Kokkedal Denmark). Objectives: To evaluate the effects of Peristeen Anal Irrigation on NBD and patient quality of life (QoL). Setting: Italy. Methods: Lesion level, ambulatory status and hand functionality were determined in all patients. NBD symptoms and QoL were evaluated before and after treatment, using a specific questionnaire. Statistical analysis was performed using McNemar Test and Sign Test. Results: Thirty-six patients were enrolled, and 32 patients completed the study. At the end of the treatment, 28.6% of patients reduced or eliminated their use of pharmaceuticals. Twenty-four patients became less dependent on their caregiver. There was a significant increase in patients' opinion of their intestinal functionality (P=0.001), QoL score (P=0.001) and their answers regarding their degree of satisfaction (P=0.001). A successful outcome was recorded for 68% of patients with fecal incontinence, and for 63% of patients with constipation. Conclusion: Peristeen Anal Irrigation is a simple therapeutic method for managing NBD and improving QoL. It should be considered as the treatment of choice for NBD, playing a role in the neurogenic bowel analogous to that of intermittent clean catheterization in bladder treatment.
KW - Constipation
KW - Fecal incontinence
KW - Neurological diseases
KW - Quality of life
UR - http://www.scopus.com/inward/record.url?scp=46749122291&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=46749122291&partnerID=8YFLogxK
U2 - 10.1038/sj.sc.3102167
DO - 10.1038/sj.sc.3102167
M3 - Article
C2 - 18317488
AN - SCOPUS:46749122291
VL - 46
SP - 517
EP - 522
JO - Spinal Cord
JF - Spinal Cord
SN - 1362-4393
IS - 7
ER -