Treatment of nodular prurigo with cyclosporin in microemulsion

S. Veraldi

Research output: Contribution to journalArticlepeer-review

Abstract

BACKGROUND: Nodular prurigo is a chronic dermatitis characterized by very intense pruritus. The treatment is often unsatisfactory. METHODS: Two patients, suffering from chronic, widespread and therapy-resistant nodular prurigo, were treated with cyclosporin in microemulsion. The drug was used orally, at dosage of 3 mg/kg per day for 2 months, followed by 2.5 mg/kg per day for 2 months and by 2 mg/kg per day for 2 months. During the therapy no other topical or systemic drugs were used. RESULTS: In both patients pruritus regressed almost completely within 2 weeks, whereas the morphology of the lesions changed slightly (minimal reduction in infiltration and erythema). The regression of pruritus was followed by a noteworthy improvement in the quality of life. During follow-up, no relapses of pruritus were reported. CONCLUSION: On the basis of this experience, cyclosporin in microemulsion can be successfully used in the treatment of chronic, widespread and therapy-resistant nodular prurigo.

Original languageEnglish
Pages (from-to)237-239
Number of pages3
JournalJournal of Dermatological Treatment
Volume10
Issue number4
Publication statusPublished - Dec 1999

Keywords

  • Cyclosporin
  • Cyclosporin in microemulsion
  • Nodular prurigo

ASJC Scopus subject areas

  • Dermatology

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