Treatment of postscabies prurigo with diflucortolone and chlorquinaldol in a group of African refugees

Stefano Veraldi, Rossana Schianchi, Luigi Esposito, Paolo Pontini, Gianluca Nazzaro

Research output: Contribution to journalArticle

Abstract

Postscabies prurigo (PSP) is caused by a delayed hypersensitivity reaction to antigens of the mite. Treatment is based on potent topical or intralesional corticosteroids. We present the results of a study on the effectiveness of a topical combination of diflucortolone and chlorquinaldol. Eighteen African patients who had been previously affected by scabies and treated with permethrin were enrolled. The diagnosis of PSP was made by excluding other causes through microscopic examinations. All patients were treated with the drug combination by two applications daily for two weeks. The primary study objective was to evaluate the itch by a visual analogue scale (VAS) of 0–100. Fifteen patients (83.3%) could be evaluated. All reported improvements: from 86/100 at the start to 29/100 (−57/100) at the end of treatment. Chlorquinaldol, known as an antiseptic agent, demonstrated, according to results of this study, an important anti-itch action.

Original languageEnglish
Pages (from-to)268-270
JournalTropical Doctor
Volume49
Issue number4
DOIs
Publication statusPublished - Jan 1 2019

Fingerprint

Chlorquinaldol
Diflucortolone
Prurigo
Refugees
Permethrin
Scabies
Local Anti-Infective Agents
Mites
Delayed Hypersensitivity
Drug Combinations
Visual Analog Scale
Adrenal Cortex Hormones
Therapeutics
Antigens

Keywords

  • chlorquinaldol
  • diflucortolone
  • postscabies prurigo
  • Scabies

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Infectious Diseases

Cite this

Treatment of postscabies prurigo with diflucortolone and chlorquinaldol in a group of African refugees. / Veraldi, Stefano; Schianchi, Rossana; Esposito, Luigi; Pontini, Paolo; Nazzaro, Gianluca.

In: Tropical Doctor, Vol. 49, No. 4, 01.01.2019, p. 268-270.

Research output: Contribution to journalArticle

Veraldi, Stefano ; Schianchi, Rossana ; Esposito, Luigi ; Pontini, Paolo ; Nazzaro, Gianluca. / Treatment of postscabies prurigo with diflucortolone and chlorquinaldol in a group of African refugees. In: Tropical Doctor. 2019 ; Vol. 49, No. 4. pp. 268-270.
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