Treatment of Pseudomyxoma Peritonei with Two Times- Cytoreduction and Hypertermic Antiblastic Peritoneal Perfusion (HAPP)

Michele De Simone, S. Scuderi, M. Vaira, D. Costamagna, R. Barone, G. Fiorentini, P. Dentico, A. Caponi, B. Ciaccio, C. Caponi, L. Ferri, E. Martini, S. Cantini

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Abstract

Pseudomyxoma peritonei is a rare neoplasia with a low grade of clinical malignity in which neoplastic masses product large amount of mucinous material. Its treatment advocates an aggressive cytoreduction of all visceral and peritoneal lesions and Hyperthermic Antiblastic Peritoneal Perfusion (HAPP). In three cases we programmed a two stage surgical approach for the massive amount of peritoneal implants. Two times we achieved our aim, while one time, the wide progression of the disease during the two surgical procedures made useless our efforts to have a complete cytoreduction and the following HAPP. This last patient refused systemic chemotherapy between the two surgeries and we think that this should be one of the reasons of the failure.

Original languageEnglish
Pages (from-to)25-28
Number of pages4
JournalJournal of Experimental and Clinical Cancer Research
Volume22
Issue number4 SUPPL.
Publication statusPublished - Dec 2003

Keywords

  • Cytoreduction
  • Intraperitoneal chemotherapy
  • Pseudomyxoma

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

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