Treatment of severe acidemia in a young woman affected by diabetic ketoacidosis.

S. Colombo, A. Casati, T. Capocasa, G. Cornero, G. Gallioli, G. Torri

Research output: Contribution to journalArticle

Abstract

The case of a 32-year-old woman admitted to Hospital for diabetic coma (GCS 8), with arterial blood pH below usually reported vital range, is described. After First Aid admittance an arterial blood gas analysis adjusted for patient's temperature showed PaO2 10.77 kPa, PaCO2 7.8 kPa, pH 6.52, HCO3 5 mmol/L, BE-34.9. A significant increase of lactate and butyrate concentration was also found. The patient was intubated and breathing was assisted for a 60 hour period after ICU admission, while acidemia was treated by THAM and bicarbonate associated to potassium i.v. infusion (infusions were titrated on acid-base and electrolyte concentration direct monitoring). After progressive neurological and biochemical improvement, 7 days after ICU admission the patient was moved to an Internal Medicine department. This case demonstrated that during diabetic ketoacidosis, despite very low pH (below reported vital range), an invasive intensive treatment could give complete cure without neurological sequelae.

Original languageEnglish
Pages (from-to)379-382
Number of pages4
JournalMinerva Anestesiologica
Volume63
Issue number11
Publication statusPublished - Nov 1997

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Diabetic Ketoacidosis
Diabetic Coma
First Aid
Blood Gas Analysis
Butyrates
Patient Admission
Internal Medicine
Bicarbonates
Electrolytes
Lactic Acid
Potassium
Respiration
Therapeutics
Temperature
Acids

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

Cite this

Colombo, S., Casati, A., Capocasa, T., Cornero, G., Gallioli, G., & Torri, G. (1997). Treatment of severe acidemia in a young woman affected by diabetic ketoacidosis. Minerva Anestesiologica, 63(11), 379-382.

Treatment of severe acidemia in a young woman affected by diabetic ketoacidosis. / Colombo, S.; Casati, A.; Capocasa, T.; Cornero, G.; Gallioli, G.; Torri, G.

In: Minerva Anestesiologica, Vol. 63, No. 11, 11.1997, p. 379-382.

Research output: Contribution to journalArticle

Colombo, S, Casati, A, Capocasa, T, Cornero, G, Gallioli, G & Torri, G 1997, 'Treatment of severe acidemia in a young woman affected by diabetic ketoacidosis.', Minerva Anestesiologica, vol. 63, no. 11, pp. 379-382.
Colombo S, Casati A, Capocasa T, Cornero G, Gallioli G, Torri G. Treatment of severe acidemia in a young woman affected by diabetic ketoacidosis. Minerva Anestesiologica. 1997 Nov;63(11):379-382.
Colombo, S. ; Casati, A. ; Capocasa, T. ; Cornero, G. ; Gallioli, G. ; Torri, G. / Treatment of severe acidemia in a young woman affected by diabetic ketoacidosis. In: Minerva Anestesiologica. 1997 ; Vol. 63, No. 11. pp. 379-382.
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